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Showing 1 to 4 of 4 for “"Coronavirus replication"”.
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Coronavirus Replication Inhibition by Herbal Extracts
Coronaviruses are plus-stranded RNA viruses that infect human and large variety of animals, including pig, cattle, dog, rat, rabbit, turkey, and bird. Human coronavirus has been known to cause common colds and perhaps gastroenteritis. Animal coronaviruses cause gastroenteritis, hepatitis, and a …
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A reverse genetics study of the Human Coronavirus 229E ADP-ribose-1"-phosphatase
Coronaviruses have extremely large RNA genomes and use complex regulatory mechanisms to replicate and express their genomes. This involves the expression of two large polyproteins, pp1a and pp1ab, that are autoproteolytically processed to produce nonstructural proteins (nsp) 1 to 16. In this study, …
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Regulation of IRF-3-Dependent Innate Immune Signaling Pathway by the PLpro Domain of Non-Structural Protein 3 (NSP3) of Severe Acute Respiratory Syndrome (SARS) Coronavirus
… effects of IFN, ensuring their survival and replication. Severe acute respiratory syndrome coronavirus (SARS-CoV) is a highly pathogenic virus that causes severe lung disease in humans and is associated with high mortality rates. SARS-CoV, like all other successful viruses, encode proteins …
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In vitro inhibition of coronavirus replications
"In Vitro Inhibition of Coronavirus Replications A search for new anti-coronaviral drugs to treat coronaviral infections was motivated by an outbreak of severe acute respiratory syndrome (SARS). In order to find drugs that treat coronavirus infections, including SARS, we screened traditional …