Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 13 of 13 for “"Corneal endothelium"”.
-
Morphological investigations into the development of the mammalian corneal endothelium using the mouse model
The corneal endothelium (CE), a mesenchyme-derived tissue, is a monolayer of squamous cells on the inner corneal surface. In Foxc1-1• mice, the CE fails to form. The understanding of the cause of this defect has implications for the study of human eye disorders that are related to FOXC1 mutations. …
-
Cloning and Sequencing of Bovine Na+/K= Atpase α-1 Sub-Unit
… the α-1 sub-unit of Na+/K+-ATase gene in bovine corneal endothelium. The Na+/K+-ATase, also called the Na+ pump, is a crucial transmembrane protein. By transporting water and ions from and through the cornea into the aqueous humor, it is responsible for maintenance of structural integrity, …
-
Μελέτη του ενδοθηλίου του κερατοειδούς στον άνθρωπο, in vivo, με τον φακό επαφής του Eisner
… we studied the changes in the middle of the corneal endothelium by the aging on one hand and by cataract surgery, with or without anterior or posterior changes lens, on the other. The first part includes the examination of 200 individuals (400 eyes) aged from 20-93 years. A gradual decrease …
-
IN VITRO MODULATION OF HUMAN CORNEAL ENDOTHELIAL CELL BEHAVIOR VIA TOPOGRAPHICAL AND BIOCHEMICAL CUES
Human corneal endothelium plays important roles in maintaining corneal transparency. However, corneal endothelial cells do not proliferate in vivo, resulting in decreased cell density over time. While the endothelium normally can sustain its function for a lifetime, trauma and diseases can result …
-
Investigation of relative expression level of SLC4 bicarbonate transporter family in mouse and Human corneal endothelial cells
… solutes and ions, crucial for the maintenance of corneal transparency. Several members (SLC4A11, SLC4A4) have been implicated in corneal diseases in human. Aim: To characterize relative expression levels of SLC4 members in mouse and human corneal endothelium, using qRT-PCR, to identify further …
-
In vivo confocal microscopy of the cornea in health and disease
… is key to these functions and maintenance of corneal integrity. In vivo confocal microscopy enables examination of the living human cornea at the microstructural level. This technique, in combination with computerized topography, corneal aesthesiometry and other clinical assessments has been …
-
Specific and efficient in vivo delivery of DNA and siRNA by polyethylenimine and its derivatives
… rabbit cornea. PEI-GNPs effectively transfected corneal endothelium and evoked expression of the plasmid DNA without causing significant immunogenicity or toxicity. Finally, the effect of radiation on biologics was evaluated using a rigorously controlled experimental design with extreme …
-
Role of IL-17A and Acaid in the Maintenance of Corneal Immune Privilege
… local immunogenic inflammation and trauma to the corneal endothelium. This local immune deviation is achieved through multiple anatomical, physiological, and immunoregulatory features intrinsic to the ocular environment that allow the cornea to enjoy an immune privileged status. Corneal immune …
-
Transcriptional profiles of differentiating periocular neural crest cells and the function of Nephronectin during chick corneal development
… of migration that result in the formation of the corneal endothelium and stroma. Abnormalities in pNC migration lead to corneal malformation, such as anterior segment dystrophy. Corneal dystrophies, infections, and injuries can lead to corneal blindness, one of the major causes of blindness. …
-
Destruction of Corneal Nerves Promotes Corneal Allograft Rejection
The human corneal endothelium has very little regenerative capacities and cannot fully heal in response to infection or trauma. Evolutionarily, the eye developed a mechanism to retain visual acuity by protecting the eye from inflammatory damage, referred to as immune privilege. The mechanisms that …
-
Hyperadaptation - Another Missing Term in the Science of Form
In a 1982 paper, Gould and Vrba argue that a conflation of the two components of adaptation of a feature, historical development of the feature and present utility, has caused evolutionists to overlook a missing term in the science of form, which they call 'exaptation'. In the present project, I …
-
Cambios en los parámetros endoteliales y del grosor central de la córnea en uveítis anterior: una revisión sistemática y metaanálisis
… entre la uveítis y los hallazgos en el endotelio corneal y el grosor central de la córnea. Métodos: Se realizó una revisión sistemática de la literatura mediante la búsqueda en múltiples bases de datos médicas, incluyendo PubMed, EMBASE, Biblioteca Virtual en Salud (BVS) y una búsqueda de …