Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Corneal Transplantation"”.
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Novel Options for the Treatment of Corneal Disease
Corneal disease leads to a significant burden of blindness worldwide and corneal transplantation remains the primary method of visual rehabilitation in this context. Corneal transplantation is the most commonly performed transplantation procedure in New Zealand with approximately 300 cases …
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Feline Leukemia Virus Detection in Corneal Tissues of Cats by Polymerase Chain Reaction and Immunohistochemistry
Corneal transplantation carries a high rate of success in the domestic cat and is an indicated treatment for specific corneal diseases in this species. The potential for iatrogenic transmission of viral diseases is a well-recognized problem in human corneal transplantation programs and screening …
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Elucidating the Genetic Basis of Fuchs Endothelial Corneal Dystrophy
<p>Fuchs endothelial corneal dystrophy (FECD) is a complex, late-onset disorder that is a frequent indication for corneal transplantation and affects women more frequently than men. Although linkage and association studies in patients of European and Asian ancestry have started to explain the …
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Role of Allergic Conjunctivitis in Inducing Corneal Transplant Rejection
Corneal allografts are the most commonly transplanted solid organs in humans and have a success rate of over 90%. This low incidence of graft rejection is largely due to the unique properties of the eye that decrease the likelihood of mounting an immune response, a phenomenon called "immune …
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Consolidating Approaches to Maximise Outcomes and Minimise Complications of Contemporary Cataract Surgery
… surgery with toric intraocular lenses to correct corneal astigmatism (N=200 eyes). This study revealed excellent visual outcomes and low residual refractive astigmatism. To assess relative dexterity in eye surgery the Eyesi® Surgical virtual reality simulator was used to evaluate the dominant hand …
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Corneal donations in South Africa: a 15-year review
Background: Corneal pathology is one of the leading causes of preventible blindness in South Africa. A corneal transplant procedure can restore, or significantly improve vision in most of these patients. In current South African clinical practice however, there is a gross shortage of corneal tissue …
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Transcriptional profiles of differentiating periocular neural crest cells and the function of Nephronectin during chick corneal development
… of migration that result in the formation of the corneal endothelium and stroma. Abnormalities in pNC migration lead to corneal malformation, such as anterior segment dystrophy. Corneal dystrophies, infections, and injuries can lead to corneal blindness, one of the major causes of blindness. …
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Destruction of Corneal Nerves Promotes Corneal Allograft Rejection
The human corneal endothelium has very little regenerative capacities and cannot fully heal in response to infection or trauma. Evolutionarily, the eye developed a mechanism to retain visual acuity by protecting the eye from inflammatory damage, referred to as immune privilege. The mechanisms that …
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Reconstitution of a Multi-layered, Differentiated Cornea by HTERT-Immortalized Corneal Epithelial Cells Transduced with Thymidine Kinase Transplanted onto Denuded Mouse Corneas
… reverse transcriptase (hTERT)-immortalized human corneal epithelial cell line (hTCEpi) transduced with the hygromycin-thymidine kinase gene (HyTK) as a viable cell source for the reconstruction of the corneal surface. METHODS: HyTK cells were cultured in KGM-2 serum-free culture media under …
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Robotics and Virtual Reality for Optical Coherence Tomography-Guided Ophthalmic Surgery and Diagnostics
… keratoplasty (DALK), a promising technique for corneal transplantation, that poses such significant manipulation and visualization challenges that 59% of procedures fail. In DALK, surgeons must insert a needle 90% through the 500 μm cornea without penetrating its underlying membrane using a …
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Role of IL-17A and Acaid in the Maintenance of Corneal Immune Privilege
… local immunogenic inflammation and trauma to the corneal endothelium. This local immune deviation is achieved through multiple anatomical, physiological, and immunoregulatory features intrinsic to the ocular environment that allow the cornea to enjoy an immune privileged status. Corneal immune …
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Corneal transplant epidemiology in a reference center in Bogotá, Colombia (2010‑2017)
… 392 sujetos (56,8%) eran hombres. Las ectasias corneales fueron la primera indicación de trasplante. La técnica más realizada fue la Queratoplastia Penetrante (QPP) (89,6%), seguida de la Queratoplastia Lamelar Anterior profunda (DALK) (5,3%), Queratoplastia endotelial (3,5%) y …