Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"Core regulatory circuitries"”.
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TCF4 Is a Key Mediator of Cell Identity and Oncogenesis in Neuroblastoma
… vulnerabilities, we characterized the TCF4 regulatory interactome and identified multiple epigenetic factors including HDACs and KDM1A. We determined that inhibitors to both HDACs and KDM1A, which often form complexes together, reduce TCF4 protein stability. Our work suggests that loss of …