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Showing 1 to 20 of 20 for “"Copper toxicity"”.
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Zinc and copper toxicity thresholds on Cellulomonas flavigena
Includes bibliographical references (pages 90-93).
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The Mechanism of Copper Toxicity in Escherichia Coli
… of this study was to determine the mechanism of copper toxicity. Copper is toxic to both eukaryotes and prokaryotes and is the causative agent of Indian childhood cirrhosis, Tyrolean infantile cirrhosis, and Wilson disease. Studies in eukaryotic systems demonstrated that copper-toxified cells had …
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Ecotoxicology and ecophysiology of mysids, with special reference to copper toxicity in Praunus flexuosus
Toxicity of dissolved copper was examined in a common coastal mysid population {<i>Praunusflexuosus</i>}. The life cycle and ecophysiology were studied under natural conditions throughout the year, and responses to dissolved copper were determined in the laboratory. Pronounced and ontogenic …
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The use of esterase activity as a measure of copper toxicity in marine microalgae
Copper is necessary for normal cellular activity, but may become toxic at high levels. Copper is widely used in North Queensland as a component of agricultural chemicals and antifouling paints, and high levels of Cu have been measured in some near-shore marine environments. Because of this, there …
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Development of a beta-Secretase Activated Prochelator and FRET Probe to Mediate Copper Toxicity in Alzheimer's Disease
… hydrolysis, the molecule is able to bind copper and reduce its toxicity both in vitro and in a cellular model of Alzheimer's Disease. </p><p>Central to this strategy is the site-specificity provided by enzymatic activation of the prochelator. In our system, SWH to CP conversion is mediated …
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Theoretical copper sulfate dosing;the effect of alkalinity and humic acid on ionic copper toxicity to algae
The chemistry of copper sulfate dosing for effective algal kill was investigated in laboratory studies with Selenastrum capricornutum and Microcystis aeruginosa. The goal was to give practical information for water treatment plants operators who often must apply copper sulfate for algae control in …
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Bioavailability models for predicting copper toxicity to freshwater organisms - Biobeschikbaarheidsmodellen voor het voorspellen van de toxiciteit van koper voor zoetwaterorganismen
Aquatische ecotoxicologie heeft als uiteindelijk doel het evalueren van risico’s van natuurlijke en antropogene stoffen voor aquatische ecosystemen. Dit proefschrift is specifiek gericht op het gebruik van toxiciteitsgegevens voor koper in zoetwater ecosystemen voor risico-evaluatie procedures en …
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Evaluation of Chelex 100 and Assessing the Impact of Fulvic Acid (NOM) on Copper Toxicity and Bioavailability to Americamysis bahia
… distinguishes weakly bound and strongly bound copper was investigated for its ability to measure bioavailable copper in estuarine waters. Copper bound to the Chelex 100 resin was operationally defined as bioavailable copper. Varying initial copper concentration from 195 to 495 ug/L at a …
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Applicability of the biotic ligand model for mining influenced waters and influence of variations in natural organic matter characteristics on copper toxicity to Ceriodaphnia Dubia
Includes bibliographical references (pages 87-91).
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The relationship between cupric ion activity and the toxicity of copper to phytoplankton
… relationship between cupric ion activity and the toxicity of copper to phytoplankton and further to study the effect on copper toxicity of naturally occurring organic ligands. Culture experiments with an estuarine diatom Thalassiosira pseudonana (clone 3H) in highly chelated seawater media …
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The effects of altered membrane fatty acid composition on the toxic interactions of heavy metals with Saccharomyces Cerevisiae
… plasma membrane permeabilisation and whole cell toxicity was markedly accentuated in PUF A-enriched cells, and increased with the degree of fatty acid unsaturation. The increased sensitivity ofPUFA-enriched cells to membrane permeabilisation and whole-cell toxicity was correlated with increased …
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Production of Copper-Complexing Ligands in Response to Elevated Concentrations of Copper in Marine <i>Synechococcus</i> spp.
… cyanobacteria) are extremely sensitive to copper toxicity and can produce high-affinity ligands of unknown structure which form complexes with free cupric ion. These ligands may contribute to the biological control of the levels of free cupric ions in surface seawater. …
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Bioorthogonal Reactions: Synthesis and Evaluation of Different Ligands in Copper Catalyzed Azide-Alkyne1,3-Dipolar Cycloaddition (CuAAC)
<p>The Copper CatalyzedAzide-Alkyne1,3-Dipolar Cycloaddition (CuAAC) reaction has unique features that qualify it to be one of the best click reactions. Its applications have been shown in different aspects and for multiple purposes. The oxidative degradation of biological systems (labile proteins …
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The effects of Hydroxypropyl-β-Cyclodextrin on the American Flagfish (Jordanella floridae) over one complete life-cycle
… a moderate 3-fold decrease in tolerance to acute copper toxicity.
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Biophysical and Functional Characterization of the Persulfide Sensor CstR from Staphylococcus aureus
… control of the transcriptional regulator CstR (Copper-sensing operon repressor (CsoR)-like sulfurtransferase repressor). In this work, sulfide stress, as exogenous H2S or RSS, is identified as a strong inducer of the cst operon. Failure to express this operon or deletions of enzymes within …
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Copper as an Antibacterial Agent and Disruptor of Protein Stability
… of new strategies to treat bacterial infections. Copper (Cu) has been used since ancient times to inhibit bacterial growth and has recently experienced a resurgence in its clinical utility as an antimicrobial coating for surfaces in hospitals. Small molecule chelators that bind Cu have also been …
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Detection and potential impacts of nanomaterials released from building materials in the natural weathering environment
… performed on two building materials, micronized copper azole (MCA) treated lumber and concrete with photoactive titanium incorporated with the cement, at five locations in the USA. MCA lumber released copper, but the amount and timing of release varied depending on the weathering climate. In …
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Interactions of Fe(II) with the iron oxidizing bacterium Rhodopseudomonas palustris TIE-1
… concentrations of iron. The cause of this toxicity was found to be dependent on copper, which is toxic to TIE-i at fairly low concentrations. Our results indicate the copper toxicity is synergistically increased by Fe(II) under strictly anaerobic conditions. The second part of this work …
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MODULATION OF TRPML1/TFEB PATHWAY FOR THE TREATMENT OF WILSON DISEASE
… recessive disorder characterized by toxic copper accumulation in several tissues, resulting in hepatic and neurological impairment. WD is caused by mutations in the P-type ATPase copper transporting B (ATP7B) gene, responsible for copper supply to cuproproteins and removal of excessive …