Global ETD Search
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Showing 1 to 10 of 10 for “"Convergent extension"”.
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The evolution of somitogenesis: Mechanisms of paraxial mesoderm elongation in zebrafish and other vertebrates
… that this tissue elongates through some form of convergent extension, not through growth. In fact, the tissue is compressed over time, and so decreases in volume. I suggest that these processes may be functionally linked, and thus propose a novel mechanism of “compression-extension”. Cell …
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Regulation of Actin Dynamics During Drosophila Germband Extension
<p>Convergent extension is a process that occurs in the development of a wide variety of organisms, including gastrulation in the <em>Drosophila</em> embryo to begin to lay out the adult body plan. In fly embryos, this is known as germband extension and is mainly driven by cell intercalation or …
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Dynamics of Cell Packing and Polar Order in Developing Epithelia
… also control developmental processes such as convergent-extension. We present a theoretical study of cell packing geometry in developing epithelia. We use a vertex model to describe the packing geometry of tissues, for which forces are balanced throughout the tissue. We introduce a cell …
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Learning from Disorder and Noise in Physical Biology
… Even at the organismal scale, germband extension (GBE) in <em>Drosophila melanogaster</em> embryos systematically elongates the epithelial tissue using cell intercalation, but leaves cells in highly heterogenous geometries. Throughout this work, we will demonstrate that these …
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The extreme anterior domain coordinates brain and craniofacial development
… Formation of the pre-mouth array involves convergent extension-like behavior where the EAD, originally a wide and short mass of cells, narrows and lengthens to form two columns of cells which later split down the middle during mouth opening. Reciprocal signaling between the EAD and neural …
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Semidefinite Cuts and Partial Convexification Techniques with Applications to Continuous Nonconvex Optimization, Stochastic Integer Programming, and Facility Layout Problems
… is on developing a first comprehensive finitely convergent extension of Benders' methodology for problems having 0-1 mixed-integer subproblems. We next address a specific challenging MIP application known as the facility layout problem, and we significantly improve its formulation through …
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CAMK-II: AN INTEGRAL PROTEIN IN CELL MIGRATION
… of the presumptive mesendoderm and convergent extension (C&E). C&E movements narrow the germ layers mediolaterally (convergence) and elongate them anteroposteriorly (extension) to define the embryonic axis. The molecular mechanisms regulating coordinated cell migrations remain poorly …
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Wnt9b Signals Through Two Distinct Pathways to Regulate Progenitor Maintenance, Differentiation and Morphogenesis During Kidney Development
… established during early morphogenetic stages by convergent extension processes and maintained by polarized cell divisions. Wnt9b, signaling through the non-canonical Rho/Jnk branch of the Wnt pathway, is necessary for both of these processes. These findings provide novel insights into the …
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How to build a chordate: Multiscale decomposition of axial morphogenesis in the amphioxus, Branchiostoma lanceolatum
… depends on tissue-specific programmes of convergent extension behaviour. Within this, volumetrically-reductive cell division acts to regulate tissue complexity via focal regulation of cell size and number, and is required in axial progenitor cells of the tailbud for full elongation of the …
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Quantitative Aspects of Interface Remodeling During Germband Extension
… to drive oriented cell intercalation and tissue extension in the <em>Drosophila</em> epithelium.</p> <p>In a second study, analysis of germband extension in 4D revealed that interface contraction and T2 formation can initiate from any point along on the apical-basal axis, including basolateral …