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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 186 for “"Contrast Agent"”.
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Dextran Magnetite as an NMR Contrast Agent
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Collapse dynamics of ultrasound contrast agent microbubbles
Ultrasound contrast agents (UCAs) are micron-sized gas bubbles encapsulated with thin shells on the order of nanometers thick. The damping effects of these viscoelastic coatings are widely known to significantly alter the bubble dynamics for linear and low-amplitude behavior; however, their effects …
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Encapsulated Contrast Agent Markers For Mri-Based Post-Implant Dosimetry
… seed localization, MRI markers with encapsulated contrast agent that provide positive-contrast on MRI images (Sirius MRI markers; C4 Imaging, Houston, TX) have been proposed to be placed adjacent to the negative-contrast seeds. This dissertation describes the development of the Sirius MRI markers …
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Examining the biophysics of ultrasound and contrast agent induced angiogenesis
… research suggests that ultrasound-ultrasound contrast agent treatment can be therapeutically beneficial, providing a noninvasive way to spatially and temporally target ischemic tissues. This type of angiogenic therapy can be used as an alternative to high risk percutaneous intervention or …
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A contrast agent for MRI of calcifications in breast cancer
… presents a hydroxyapatite-targeted gadolinium contrast agent for UTE MRI of calcification in malignant breast cancer. The hydroxyapatite-targeted contrast agent was synthesized by conjugating a bisphosphonate, pamidronate, to a gadolinium chelate. Binding specificity was tested by UTE MRI of …
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Attachment mechanisms of a novel, targeted, lipid-based, ultrasound contrast agent
… targeted, lipid-based, microbubble ultrasound contrast agent (UCA) for assessment of coronary heart disease (CHD) with high frequency intravascular ultrasound (IVUS). The targeting mechanisms assessed for microbubble attachment include a streptavidin-biotin mechanism, electrostatic mechanism …
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Liposome Encapsulated Manganese Chloride as a Liver Specific Contrast Agent for Magnetic Resonance Imaging
… encapsulated paramagnetic ion (Mn$\sp{2+}$) as a contrast agent for magnetic resonance imaging (MRI) of the liver. Previous work with liposomes had shown that liposomes were concentrated in the liver after intravenous injection. Uptake of the vesicles into tumors was shown to be negligible. This …
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Calculation of the effective atomic number for the iodine contrast agent of the varying concentrations
… of the concentration of the iodinated contrast agents in the blood stream via the traditional gray-scale computer tomography and searches for the new imaging modalities that would provide for better sensitivity. The topic of the energy-discriminative color CT is discussed as a potential …
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Engineering functionalized gold nanoparticles as a molecular-specific contrast agent to enhance optoacoustic detection of breast cancer cells
… including breast. Delivering molecular specific contrast agents to breast cancer cells would enhance the sensitivity and specificity of imaging methods to detect cancer foci at earlier stages, when complete cure is possible. Optoacoustic tomography (OAT) is a non-invasive imaging modality that …
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Developing a Microbubble-based Contrast Agent for X-ray Phase Contrast Imaging to Detect Neovasculature in Breast Cancer
X-ray phase contrast imaging (XPC) generates contrast from refraction and scattering of X-rays, unlike absorption in conventional radiology. This technique greatly improves the sharpness of boundaries and reveals micro-structured tissues that are not easily detected by conventional absorption-based …
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Investigation of a Potential Macromolecular MRI Contrast Agent Prepared From PPI (G = 2, Polypropyleneimine, Generation 2) Dendrimer Bifunctional Chelates
… imaging of this complex resulted in a 52% contrast enhancement in the rat kidney following the agents' administration in vivo.
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UV- TiO2 photocatalytic degradation of the x-ray contrast agent diatrizoate: kinetics and mechanisms in oxic and anoxic solutions
In recent years, triiodinated X-ray contrast agents (XRCs) have been widely detected in natural waters at concentrations that are often relatively high compared to other pharmaceutical micropollutants due to their extensive use and high biological recalcitrance. Diatrizoate is an ionic XRC that has …
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Application of a High‑Resolution Computed Radiography System in Detecting an Iodinated X‑ray Contrast Agent: Small Animal Phantom Study
… and crucial for their development. Iodinated contrast agents are used to increase the X‑ray detectability of zone of angiogenesis, and thus providing a means for tracking tumor growth.</p> <p>The overall objective of this project was to evaluate the performance of Kodak CR 7400, a …
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The Use of Ultrasound-Targeted Microbubble Destruction in Mediated Delivery of a Gadolinium Magnetic Resonance Imaging Contrast Agent Into Fibroblast Cells In Vitro
A method for delivering Gd-based MRI contrast agents by ultrasound-targeted microbubble destruction into fibroblast cells in vitro is presented. First, MRI contrast agents Gd-F-DOTP-ME and Gd-DOTA-4iBA are shown to associate with liposome microbubbles used as ultrasound contrast agents. Repeated …
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The Development of a Novel Tumor -Specific MRI Contrast Agent Targeting the High Affinity Folate Receptor: In Vitro and in Vivo Specificity, Toxicity, and Biodistribution
The need to develop target-specific MRI contrast agents to aid in disease characterization remains highly essential. Here, we present a generation four polyamidoamine (PAMAM) dendrimer conjugated to folic acid that specifically targets the high affinity folate receptor (hFR) overexpressed on more …
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ESTIMATING PERFUSION AND VASCULAR PROPERTIES FROM MEDICAL IMAGES: QUANTITATIVE TRANSPORT MAPPING (QTM)
… affect organ function. Under this circumstance, contrast enhanced medical imaging techniques were developed, where contrast agents are injected into human body (alternatively, spin labeled water molecule can also work as contrast agent), and then images are acquired while contrast agent travels …
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