Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 68 for “"Contact lenses"”.
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Therapeutic contact lenses for extended drug delivery
… interest in hydrogel-based drug-eluting contact lenses as platforms for topical ocular drug delivery. These devices have shown to provide an increased residence time of drugs at the surface of the eye, leading to enhanced bioavailability (~ 50%) when compared to eye drops (1–5%). One …
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Tear protein interaction with hydrogel contact lenses
… instantaneously when a biomaterial comes into contact with most biological fluids. The eye is a unique body site for the study of protein interactions with biomaterials, because of its ease of access and deceptive complexity of the tears. The use of contact lenses for either vision correction …
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Acrylamide Based Hydrogels for Continuous Wear Contact Lenses
… to meet the requirements of a continuous wear contact lens material. This has been achieved by making a number of chemical modifications to a simple acrylamide-based copolymer in order to produce a material of appropriate water content, oxygen permeability, mechanical strength, and long-term …
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The Role of Corneal Astigmatism When Fitting Orthokeratology Contact Lenses
… thesis was to assess the fit of sphere and toric lenses and quantify the amount of corneal astigmatism corrected, and to determine the effect of peripheral elevation and central corneal astigmatism on toric orthokeratology fitting. Methods: Two different studies were performed. The first was a …
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Photosensitizer Loaded Contact Lenses As An Externally Stimulated Ophthalmic Drug Delivery System
Ophthalmic administration of drugs is primarily associated with the treatment of ocular diseases. 90% of the ophthalmic dosage forms are given topically. However, following the topical route, only 5% ocular bioavailability is achieved. The aim of my work is to address the problems associated with …
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Mechanics and materials issues in processing and flexibility of soft contact lenses
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1995.
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Changes in tear film biochemistry in end of day ocular discomfort with and without contact lenses
An estimated 30% of contact lens (CL) wearers suffer from discomfort which is more common and aggravated in the evening. This work examined changes in tear film proteins and lipids, especially those previously associated with non-contact lens dry-eye or inflammation, for their diurnal variation and …
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A novel plasma etching and emission monitoring system (PEEMS) to assess protein and lipid spoilation for hydrogel contact lenses
… and lipoidal deposition on the surface of contact lenses and highlighted the probability that penetration of these spoilants will occur. This technique developed here allows unambiguous identification of the depth of penetration of spoilants to be made for various material types. It is for …
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ΦΑΚΟΙ ΣΥΝΕΧΟΥΣ ΧΡΗΣΕΩΣ ΣΕ ΜΕΤΕΓΧΕΙΡΗΤΙΚΗ ΑΦΑΚΙΑ
… RESULTS OBTAINED FROM THE USE OF EXTENDED WEAR CONTACT LENSES IN APHAKIC PATIENTS OF THE EPIRUS AREA, 120 PATIENTS WITH EXTENDED WEAR CONTACT LENSES HAVE BEEN EXAMINED FOR A PERIOD OF 3 TO 40 MONTHS.
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Lipoidal species in ocular spoilation processes
Tear component deposition onto contact lenses is termed `spoilation' and occurs due to the interaction of synthetic polymers with their biological fluid environment. Spoilation phenomena alter the physico-chemical properties of hydrophilic contact lenses, diminishing the optical properties of the …
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Development of a non-destructive fluorescence technique for analysis of contact lens deposition levels
… a method for analysis of surface deposition on contact lenses. In order to achieve this it was first necessary to ascertain whether fluorescence analysis would be able to detect and distinguish between protein and lipid deposited on a lens surface. In conjunction with this it was important to …
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Ocular biotribology and contact lens lubrication mechanisms
… in this thesis is concerned with mechanisms of contact lens lubrication. There are three major driving forces in contact lens design and development; cost, convenience, and comfort. Lubrication, as reflected in the coefficient of friction, is becoming recognised as one of the major factors …
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Evaluating modeling techniques for quantifying production risk in contact lens manufacturing
… Vision (JJV) is a leading manufacturer of contact lenses offering a variety of vision correction products. They have a strong commitment to innovation--defining new product categories and improving existing ones--to better patient outcomes, but this poses a challenge for machine production …
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The tear film and contact lens wear
Contact lenses have become a popular method of vision correction for millions of people globally. As with all devices designed for use within the body, interactions occur between the implanted material and the surrounding biological fluid. A common complaint of lens wearers is that they often …
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Leveraging flexible manufacturing to streamline new product launch processes
… Vision (JJV), manufacturer of the ACUVUE® Brand Contact Lenses, is committed to launching new contact lens products every year to maintain competitive edge and long-term relevancy. However, manufacturing lines currently operate at high utilization rates to satisfy steadily growing demand, …
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Factors associated with soft contact lens replacement noncompliance of wearers in Windhoek
… and twenty five million people worldwide wear contact lenses (Barr, 2006). The contact lens market is increasing at an alarming rate globally and Namibia is no exception, but there are no known national statistics. Soft contact lens wearers do not comply to their specific lens replacement …
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Contact Lenses as Optical and Protective Element of the Front Ocular Surface. Issues and Future of Contactology in Bulgaria, the Balkans and Europe // Контактните лещи — оптичен и протективен елемент на предната очна повърхност. Контактологията в България, на Балканите и в Европа — проблеми и перспективи
Главна цел на настоящото проучване е да се тестват и установят стандарти за добра контактологична практика в България, съобразени с Европейската и световната контактология чрез: определяне на познанията за контактните лещи сред популацията в България и на Балканите, дефиниране на характеристиките …
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Cellular interaction with novel biomaterials
… cell adhesion to the posterior surface of a contact lens when compared to the anterior surface. Group IV contact lenses adhere more cells than Group II contact lenses - this may indicate that more protein (including vitronectin) is able to adhere to the contact lens due to the Group IV …
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