Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 226 for “"Constriction"”.
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Basal constriction : shaping the vertebrate brain
… morphogenesis. These shape changes include constriction and expansion of the cell surfaces, elongation or shortening of the apical-basal length, or cell spreading. In this thesis, I present the first description of basal constriction, a process by which cells narrow on their basal surfaces …
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High constriction ratio continuous insulator based dielectrophoretic particle sorting
… on their surface dielectric properties. A 3D constriction is fabricated inside Poly (methyl methacrylate) (PMMA) channels using a micromilling technique. By controlling the channel geometry at the 3D constriction area, a nonuniform electric field with a large intensity gradient perpendicular …
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Multi-Constriction Microfluidic Sensors for Single-Cell Biophysical Characterization
Cancer is a major health issue that has been associated with over 80 million deaths worldwide in the last decade. Recently, significant improvements have been made in terms of treatment and diagnosis. However, despite these advancements there is still a demand for low-cost, high-accuracy, and …
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Rab35 Centered Membrane Trafficking Pathway Directs Apical Constriction During Drosophila Gastrulation
… the prospective mesoderm is driven by the pulsed constriction of apical surfaces. Here, we address the mechanisms by which the irreversibility of pulsed events is achieved while also permitting uniform epithelial behaviors to emerge. We use MSD-based analyses to identify contractile steps and find …
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Molecular organization of the actin cortex in apical constriction and epithelial folding
Actin and myosin generate contractile forces to change tissue and cell shape. These shape changes are essential for many biological functions, ranging from muscle contraction to tissue morphogenesis in development. While the spatial organization and composition of the actin and myosin contractile …
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Design of multiple constriction ratio microfluidic channels for 3D insulator based dielectrophoretic chips
… be promising in its development. Using multiple constrictions of area to generate gradients of electric fields allows a device to be made without electrode arrays and at a cheaper cost. The possibility of making devices with multiple constrictions within them is undertaken using micromachining …
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Numerical Analysis of Respiratory Aerosol Deposition: Effects of Exhalation, Airway Constriction and Electrostatic Charge
… II: In order to evaluate the effects of bronchoconstriction under exhalation conditions, normal and constricted pediatric airway models were considered. Results include (i) a significant increase in deposition for constricted airways, and (ii) a novel correlation for deposition during exhalation …
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An experimental study of the wall characteristics of a local fluid constriction plasma generator
A local energy conversion efficiency for a confined-discharge plasma generator is defined as the fraction of local power input which is transferred to the gas. The local efficiency is a maximum near the gas inlet and diminishes with axial distance. The thermal development length is the axial extent …
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Direction-dependent constriction flow in a poroelastic solid : a model of the intervertebra disc valve
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1997.
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Cardiovascular magnetic resonance characterisation of myocardial involvement in tuberculous pericardial constriction with and without HIV co-infection
Background:Tuberculous pericarditis includes the spectrum of pericarditis caused by Mycobacterium tuberculosis manifesting with pericardial effusion, cardiac tamponade, effusive-constrictive and constrictive pericarditis. In patients with pericardial tuberculosis, co-infection with human …
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Mechanisms of myosin regulation and function during tissue folding
… the embryo constrict their apical sides. Apical constriction drives the formation of a furrow that invaginates, forming a tube, and consequently, a new cell layer in the embryo. Constriction of ventral cells is driven by cycles of assembly and disassembly of actin-myosin networks at the cell …
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Modelling multivariate longitudinal outcomes and time-to-event data
… duration (ECGqrsd) on survival outcomes, death, constriction, and composite outcome (death, constriction, or cardiac tamponade, whichever occurs first) in the investigation of the management of pericarditis (IMPI) in a multi-centre clinical trial. The ECG characteristics from the IMPI trial were …
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Design and testing of an experiment to measure self-filtration in particulate suspensions
… of change in volume fraction downstream of a constriction compared to volume fraction upstream of said constriction was designed and tested. The user has the ability to control a variety of parameters including constriction geometry, flow rate, and initial volume fraction in order to evaluate …
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An analysis of the role of microtubules during tubulogenesis in Drosophila
… embryo, which are formed by coordinated apical constriction and invagination of a polarised epithelial placode, as a model to understand these changes. The role of microtubules (MTs) during morphogenetic processes such as this are not well understood. In order to ascertain their role in …
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Branch junction constriction and hydraulic limitation in two species in the Cape Proteaceae : a mechanism explaining the trade-off between longevity and degree of ramification in the Cape Proteaceae
… if hydraulic limitation and branch junction constriction explain the trade-off between longevity and increased ramification in species of the Cape Proteaceae. This was done by establishing if branch nodes are regions of greater resistance to xylem sap flow in the study species; attempting to …
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Mechanisms of Actomyosin Contractility in Cells
… develop a mathematical model to characterize the constriction mechanism of contractile rings in the Schizosaccharomyces pombe model organism. Our collaborators observed that after digesting the cell wall to create protoplasts, contractile rings constricted by sliding along the plasma membrane …
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