Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Conserved Networks"”.
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Identifying Evolutionarily Conserved Protein Interaction Networks
Our goal is to investigate protein networks conserved between different organisms. Given the protein interaction networks for two species and a list of homologous pairs of protein in the two species, we propose a model for measuring whether two subnetworks, one in each protein interaction network, …
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Discovering GCNA: A Novel Regulator of Germline Genomic Stability
… Germ Cell Nuclear Acidic Peptidase (GCNA) as a conserved regulator of genome stability across multiple species. Loss of GCNA results in replication stress, chromosomal instability, and an accumulation of DNA-protein crosslinks (DPCs). Disruption of GCNA leads to an accumulation of nuclear Top2 …
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Systems Biology of Host-Pathogen Protein-Protein Interactions
… to systematically characterize SARS-CoV-2-human networks for a detailed understanding of SARS-CoV-2 pathogenesis. The angiotensin-converting enzyme (ACE2) receptor of SARS-CoV-2 is displayed on many human cells, including the lungs and other organs. However, despite considerable knowledge …