Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 79 for “"Connectome"”.
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Uncovering the Connectome
<p>Over the past two decades, there has been an explosion in the number of tools and technology available to neuroscientists. With the advent on array tomography (AT) in the last decade, our ability to study synapses and their proteometric composition in the mammalian cortex has skyrocketed. …
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Connectome-Constrained Artificial Neural Networks
… BNN constraints onto ANNs. We select explicit connectome topologies from the fruit fly (one of the smallest BNNs) and impose these onto a multilayer perceptron (MLP) and a reservoir computer (RC), in order to craft “fruit fly neural networks” (FFNNs). We study the impact on performance, …
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High performance data processing pipeline for connectome segmentation
… try to understand the brain and reconstruct its connectome. Automated connectome reconstruction from high resolution electron miscroscopy is a challenging problem, as all neurons and synapses in a volume have to be detected. A mm3 of a high-resolution brain tissue takes roughly a petabyte of …
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Building and characterising the neuropeptidergic connectome of Caenorhabditis elegans
Nervous systems consist of synaptically-wired neuronal circuits, each with distinct roles and patterns of activity. At the level of the entire organism, these circuits integrate into a broader architecture, which is crucial for proper function. This synaptic circuitry is further modulated by …
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Connectome and Ultrastructural Studies of an Anthozoan Planula: Exaiptasia diaphana
… to their putative functional architecture. The connectome reveals that interneurons serve as central integrators, while direct sensory-to-motor pathways are absent. Only a limited number of cell types communicate via chemical synapses, suggesting neuropeptides are still the primary communication …
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Parallel and scalable neural image segmentation for connectome graph extraction
… same object, is one of the major challenges in connectome extraction. Since connectomics data consist of large quantity of digital information generated by the electron microscope, there is a necessity for a highly scalable system that performs segmentation. To date, the state-of-the-art …
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Novel Implementation of Additive Manufacturing to Visualize the Human Brain Connectome
… to create real life models of the human connectome. The human connectome is a color coded map of the connections in the human brain where directions are indicated by colors and the density of connections are indicated by color intensity.</p> <p>There are several different algorithms for …
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Graph theory analysis of functional and structural connectome: Links to Auditory Processing Disorder
The aim of this thesis was to provide insight into the functional and structural organisations in school-aged children with and without a clinical diagnosis of auditory processing disorder (APD) using the network neuroscience approach and neuroimaging techniques such as functional magnetic …
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Genetic effects on the temporal organization of connectome dynamics and associated cognitive functions
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms
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Genetic effects on the temporal organization of connectome dynamics and associated cognitive functions
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms
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Modélisation locale en imagerie par résonance magnétique de diffusion : de l'acquisition comprimée au connectome
L’imagerie par résonance magnétique pondérée en diffusion est une modalité d’imagerie médicale non invasive qui permet de mesurer les déplacements microscopiques des molécules d’eau dans les tissus biologiques. Il est possible d’utiliser cette information pour inférer la structure du cerveau. Les …
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Exploring the functional organization of cerebral cortex using data from the Human Connectome Project
… analyses. In recent years, the Human Connectome Project (HCP) has released high-quality imaging datasets from an unprecedented number of subjects. The surface-based analysis of HCP data provides a unique opportunity to investigate detailed topography of structural features and …
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Uncovering Dynamic Semantic Networks in the Brain Using Novel Approaches for EEG/MEG Connectome Reconstruction
… concreteness. Furthermore, examining whole-brain connectomes using measures of graph theory revealed modules in the right ATL and parietal cortex as global hubs; 3) Brain oscillations associated with perception and action in low-level cortices, in particular Alpha and Gamma rhythms, were modulated …
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Functional Connectivity Within the Dynamic Pain Connectome Underlying Inter-Subject Differences in Acute and Chronic Pain
Pain is an individual experience. Given an identical noxious stimulus, some individuals perceive a high level of pain, whereas others perceive minimal pain. Even when a similar level of pain is experienced, individuals’ response to its perception varies. Some people focus on the pain at the …
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Ongoing large-scale connectome dynamics across neural timescales and their moment-to-moment impact on perception
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms
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Characterising the structural brain connectome in Alzheimer's disease and its relation to cognitive intra-individual variability.
… white matter (WM) degeneration and structural connectome disruptions measured by diffusion tensor imaging (DTI) as well as increased reaction time intra-individual variability (RT IIV) on neurocognitive testing. However, the relationship between these changes measured on these different …
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Connectome-based predictive modeling of fluid intelligence: Evidence for a global system of functionally integrated brain networks
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2025-05-01
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Exploring the Cephalopod Brain: Towards Mapping the First Whole Brain Connectome and Whole Animal Projectome of a Pygmy Squid
… which are essential for a whole-brain connectome of 0.25 mm3. At the time of writing this thesis, a whole-brain volume at a resolution of 4*4*40 nm (XYZ) is being acquired using a Multibeam SEM. This volume will be the first high-resolution electron microscopy volume of a whole brain of …
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Moment-to-moment Variability of Intrinsic Functional Connectivity and Its Usefulness
… than temporal features of connectivity changes (connectome variability). The primary goal of the current study was to investigate the effectiveness of using the connectome variability in classifying an individual’s pathological characteristics from others and predicting psychosocial …
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Deterministic Barcoding of Neuron Identities through Multicolor Fluorescent Markers in C. elegans
Mapping the connectivity of neurons, or the brain connectome, with a clear identification of neuron types and functions is a complicated problem that hinders the development of potential therapeutic interventions. Without understanding the identities of neurons that have fundamental roles in …
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