Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Congo Red"”.
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Reactions of Congo Red and Azo Dye Congeners With Formaldehyde
Analysis of samples of Congo Red dye exposed to formaldehyde were found to form multiple products, including a colorless benzimidazole form previously characterized and an unidentified yellow compound. Congeners equivalent to half of the symmetrical Congo red molecule and related structures were …
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The molecular basis of pancreatic amyloid deposition in type II diabetes and the binding of congo red to amyloid
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1995.
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Antibiotic Effects of Dimethyl Sulfoxide and Synthetic Polyphenols on E. Coli Cells
… polyphenols, such as curcumin, have garnered tremendous attention. However, synthetic polyphenols commonly used in biochemistry experiments have not been sufficiently explored. The purpose of this study is to determine the effect of dimethyl sulfoxide on the cellular uptake of synthetic …
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Development of microbial control for lepidopteran pests of the corn ear
… either had no effect on mortality when compared to either pathogen alone or mortality of the virus was reduced with the addition of Bt;In the field, applications of the three entomopathogens, Javelin, XenTari, and AfMNPV, significantly decreased damage by H. zea and increased the percentage …
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Studies of Structure, Dynamics, and Interactions of Amyloid Fibrils by Magic Angle Spinning Solid State NMR
… state NMR experiments, and analyzed and compared the secondary structures of WT and deletion mutants. In Chapter 3, we designed a new approach to study the intermolecular dynamics of amyloid fibrils by an Alzheimer’s ß peptides, Aß40. By using a double quantum filter dipolar recoupling method …
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Photocatalytic Reactor using TiO2 Thin Film on Quartz Tubes
… photocatalytic reactor in degradation of congo red, KI and Nitro phenol.</p>
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Developing peptide-based inhibitors of amylin aggregation as a novel treatment for type 2 diabetes
… sheet structures which are considered to be cytotoxic to pancreatic -cells. Inhibiting the early stages of amylin aggregation could provide a potential therapeutic strategy for the treatment of type 2 diabetes. In this study, overlapping peptides were designed to target the binding …
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Membrane fragmentation by a 20-29 fragment of human islet amyloid polypeptide and rat amyloid polypeptide
… to peptide aggregation as the presence of Congo red, an inhibitor of amyloid formation, prevented membrane fragmentation, and the non-amyloidogenic rat IAPP did not cause membrane fragmentation. DSC studies suggest membrane disordering is caused by both fragments of peptides, possibly due …
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Curli Production and ERIC-PCR Fingerprinting of Escherichia coli from Clinical Cases of Bovine Mastitis
… for their ability to produce curli by binding Congo-red dye. The effect of curli production on case recovery, based on a return to milk production, was investigated for a subset of 43 isolates from 20 quarters of 19 cows. Fifty-eight of the 61 isolates were clustered into two clonal groups at …
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Antibacterial Evaluation of Polygonum Multiflorum
… anti-biofilm formation was studied using a Congo-red assay, and biofilm quantification was acquired through crystal violet assay. Finally, Chinese Knotweed was evaluated on the effects of inhibiting sporulation and germination of B. megaterium. The results suggest Chinese Knotweed contains …
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Ein Beitrag zum Vorkommen von Yersinia enterocolitica in Hackfleisch und Fleischerzeugnissen vom Schwein im Hinblick auf die eingesetzten Kultur- und Isolierungsverfahren
… and the pathogenicity was confirmed with Congo red binding and Calcium dependence on CRMOX agar plates. Pathogenic Y. enterocolitica was recovered from raw meat products but not from heat-treated products. The isolation rate of Y. enterocolitica 4/O:3 in minced meat was 9.0%. This type was …
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Evaluation of F-18 Labeled Hydroxy Quinoline Derivative as a Potential PET Imaging Agent for Early Detection of Alzheimer’s Disease
… Based on the amyloid cascade hypothesis, congo red and thioflavine derivatives have been investigated as potential PET ligands that bind specifically to the amyloid plaques. Another hypothesis, the metal hypothesis, suggested that elevated level of metals particularly zinc, copper and …
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Field Amplified Sample Stacking on Amyloid Beta (1-42) Oligomers using Capillary Electrophoresis
… widths and increased peak heights on the CE compared to the non-FASS conditions. Furthermore by conducting thioflavin-t (ThT) assays, it was observed changing the buffer concentrations in accordance to the FASS technique conditions did not effect the overall aggregation. Thioflavin-t (ThT) assays …
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Techniques for the identification and differentiation of Cronobactor species
… with regard to taxonomic changes that occurred within the genus in 2013. This work showed that these methods may not be sufficient for accurate and specific detection and identification of all Cronobacter spp. Next, the DNA sequence-based method of multilocus sequence typing (MLST) was used …
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Purification and characterisation of novel recombinant β-glucosidases from aspergillus with application in biofuel production
… bacterial proteins. A rapid plate assay based on Congo red methods was developed to study the optimum parameters such as pH and temperature for growth of strains and activities of the enzymes produced. Bacterial cellulose (BC) was produced by Gluconacetobacter xylinus. For the first time a fully …
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Monocytes as Gene Therapy Vectors for the Treatment of Alzheimer’s Disease
… to the brains in AD transgenic mouse models compared to non transgenic mice. As an approach to increase expression of NEP in a transgenic mouse model of AD, we developed an ex vivo gene therapy method utilizing bone marrow monocytes from GFP mice. These monocytes were transfected with a NEP …
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Elucidation of the Specificity of Neuroactive Steroids and Related Compounds at the at the Vesicular Glutamate Transporter
… (i.e., VGAT, VMAT). Two molecules, 5,6-QDC and Congo Red Fragment (CRF) were aligned to the VGLUT Pharmacophore to illustrate the SAR of these compounds. Biochemical studies have also been conducted to delineate substrate activity of neuroactive steroids and related compounds at VGLUT. The …
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Elucidation of the Specificity of Neuroactive Steroids and Related Compounds at the at the Vesicular Glutamate Transporter
… (i.e., VGAT, VMAT). Two molecules, 5,6-QDC and Congo Red Fragment (CRF) were aligned to the VGLUT Pharmacophore to illustrate the SAR of these compounds. Biochemical studies have also been conducted to delineate substrate activity of neuroactive steroids and related compounds at VGLUT. The …
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Characterizing induced gene expression in Shigella flexneri following bile salt exposure
… ability and intracellular replication. The Congo red (CR) secretion assay was also used as a measure of virulence protein secretion from the type-III secretion system (T3SS), while interleukin-8 (IL-8) secretion from infected HT-29 cells was measured as a marker for the epithelial cell …
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The Role of the Extracellular Matrix components of Salmonella enterica serovar Typhimurium Biofilms in Biofilm Formation and Architecture via in vitro analysis
… characterized the colony biofilm morphology by Congo red-Coomassie blue staining and the biomass in pellicle biofilms by crystal violet assay. Next, we utilized a computational 4D approach that was developed in collaboration with the Quiesser and Buttaro Labs to identify the contribution of each …
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