Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"Congenital hypothyroidism"”.
-
The epidemiology of congenital hypothyroidism in the United Arab Emirates
The newborn screening for congenital hypothyroidism (CR) started in the West in the sixties. The guidelines for screening were introduced in the majority of western countries some 30 years ago and were adapted in 1997 by the World Health Organization. The United Arab Emirates (UAE) started newborn …
-
Functional Characterization of the C-terminal Cholinesterase-Like (ChEL) Domain of the Thyroid Hormone Precursor Protein
… (AChE). Mutations in Tg cause congenital hypothyroidism, the most common congenital endocrinopathy affecting 1 in 2,000-4,000 newborns, with a varying degree of phenotypic manifestations. Tg protein, regulated by TSH, is secreted to the lumen of thyroid follicles, where …
-
Considering consent : an analysis of factors influencing parental perceptions of decisional quality in the context of newborn screening
… babies are screened for phenylketonuria (PKU), congenital hypothyroidism (CH), sickle cell diseases (SCD), cystic fibrosis (CF) and medium chain acyl-CoA dehydrogenase deficiency (MCADD), with Duchenne muscular dystrophy (DMD) offered as additional screen in Wales. Much has been written about …
-
Central disorders of thyroid function: clinical, radiological and genetic phenotyping
… mutation in the TRHR gene giving rise to central congenital hypothyroidism (CCH) are presented. In the first chapter, an overview of central disorders of thyroid function are discussed with emphasis on TSHomas and congenital central hypothyroidism. Pituitary imaging modalities are also discussed …
-
Determination of reference intervals and decision limits for thyroid stimulating hormone and thyroxine on cord blood samples
Background: Congenital hypothyroidism (CH) is a significant health concern globally, with severe consequences if left untreated. Newborn screening (NBS) programs play a pivotal role in early detection and intervention of CH. However, due to resource constraints, South Africa lacks a national NBS …
-
Development of Cochlear Nonlinearities in Normal and Tshr Mutant Mice
… characterize the physiological basis of hypothyroidism induced otopathology. To accomplish these goals, the development of auditory function was studied in both normal mice (BALB/c) and a strain commonly referred to as the hyt, or Tshr mouse. The Tshr mouse expresses a naturally occurring …
-
Α-ΦΕΤΟΠΡΩΤΕΙΝΗ ΚΑΙ ΣΥΓΓΕΝΗΣ ΥΠΟΘΥΡΕΟΕΙΔΙΣΜΟΣ
A-FETOPROTEIN (A-FP) WAS MEASURED IN DRIED BLOOD SPOTS TAKEN BY HEEL PRICK FROM525 NORMAL, 77 HYPOTHYROID AND 213 TRANSIENT HYPERTHYROTROPINAEMIC (TH) NEONATES. THE BLOOD SPOTS WERE COLLECTED AT THE TIME THE NEONATES WERE DISCHARGED FROM THE MATERNITY UNIT, I.E. BETWEEN 3RD AND 7TH DAY OF LIFE. …