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Showing 1 to 20 of 23 for “"Conditioned place preference (CPP)"”.

  1. The effects of dopamine D1 and D2 antagonists on cocaine-induced CPP in preweanling rats

    Pruitt, Douglas L.

    The effects of dopamine D1 and D2 antagonists on conditioned place preference (CPP) and locomotor activity were assessed. A total of three experiments were conducted. In each experiment there were two conditioning days followed by a test day. The results indicate that DA D1 and D2 receptors have …

    csusb-retro Repository record

  2. The effects of dopamine D1 and D2 antagonists on cocaine-induced CPP in preweanling rats

    Pruitt, Douglas L.

    The effects of dopamine D1 and D2 antagonists on conditioned place preference (CPP) and locomotor activity were assessed. A total of three experiments were conducted. In each experiment there were two conditioning days followed by a test day. The results indicate that DA D1 and D2 receptors have …

    csusb Repository record

  3. The role of amygdala group I mGluRs in synaptic plasticity and conditioned place preference in rodents

    Kady B. SchmidtThe University of Texas Medical Branch2007

    … (mGluR) antagonists can block the induction of conditioned place preference (CPP), a measure of cocaine seeking behavior, but their functions after clinically relevant withdrawal periods are not known. Our study showed that group I mGluR antagonists failed to block the expression of …

    utmb Repository record

  4. Zebrafish and Conditioned Place Preference: A Translational Model of Drug Reward

    Collier, Adam Douglas2015

    … disorder). Behavioral quantification within the conditioned place preference (CPP) paradigm serves as a measure of the rewarding qualities of a given stimulus (e.g., drug). If animals develop an increase in preference to spend time in an environment that had previously been paired with drug …

    usm Repository record

  5. Evaluating preference-seeking and aversive qualities of Salvia divinorumand Mitragyna speciosa

    Loria, Melissa Jane2020

    … liabilities. This study sought to utilize Conditioned Place Preference (CPP) to quantify rewarding or aversive properties of botanicals and their constituents in rats. This paradigm is based on the notion that animals prefer distinct environments previously paired with rewarding drugs. Our …

    mississippi Repository record

  6. Taurine's effect on cocaine reward and neurogenesis in the adolescent male rat brain.

    Villa-Gonzalez, Avery E2017

    … in attenuating the reward value of cocaine in a conditioned place preference paradigm, independent of hormonal status. Taurine has also been shown to be a neuroprotectant and neurogenic. In these studies, taurine was tested as a protectant against cocaine reward by increasing neurogenesis in the …

    cuny Repository record

  7. Serotonergic Circuits Mediating Stress Potentiation of Addiction Risk

    Fontaine, Harrison2021

    … blocked stress-induced potentiation of cocaine conditioned place preference (CPP). Within the dorsal raphe nucleus (DRN), two overlapping populations of KOR-expressing neurons: Slc17a8 (VGluT3) and SERT, were distinguished functionally and anatomically. Optogenetic inhibition of these SERT+ …

    washington Repository record

  8. Learning to be a cocaine addict: behavioral, pharmacological, and molecular characterization of individual differences in initial learning of cocaine-environment associations

    Adriane M dela CruzThe University of Texas Medical Branch2009

    … associations. We utilized the conditioned place preference (CPP) paradigm in laboratory rats to model cocaine-environment associations and developed a new method for the analysis of CPP data that allows for identification of factors that modulate individual sensitivity to the …

    utmb Repository record

  9. EARLY ADOLESCENT NICOTINE EXPOSURE HAS LONG-LASTING EFFECTS ON COCAINE-INDUCED BEHAVIORS IN MICE

    ALAJAJI, MAI2018

    … effects of several drugs of abuse in the conditioned place preference (CPP) test. Furthermore, we predict that these changes in behavioral responses are mediated by nicotine-induced brain region-specific increases in the expression of ΔFosB, a member of the Fos family of transcription …

    vcu Repository record

  10. INVESTIGATING THE ROLE OF α6 and α4 CONTAINING NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS IN NICOTINE AND COCAINE CONDITIONED PLACE PREFERENCE TESTS IN MICE.

    Sanjakdar, Sarah2017

    … in nicotine and cocaine reward using an unbiased conditioned place preference (CPP) test in mice. Adult male C57BL/6J mice or male mice null for the α6 or α4 nicotinic receptor subunit were used. For CPP: On day 1, pre-conditioning scores were recorded; Days 2-4 mice underwent conditioning, where …

    vcu Repository record

  11. The Role of MAGL Inhibition in Nicotine Withdrawal and Reward

    Muldoon, Pretal2022

    … of nicotine reward as measured in the mouse conditioned place preference (CPP). In contrast to withdrawal, JZL184’s effect on nicotine CPP was not CB1 mediated. In addition, JZL184 treatment did not cause significant alterations in CB1 receptor levels or receptor-mediated G-protein activity …

    vcu Repository record

  12. Gabab Regulation of Methamphetamine-Induced Associative Learning

    Voigt, Robin Michelle2016

    … the incidence of cue-elicited relapse.</p><p>Conditioned place preference (CPP) is a behavioral paradigm in which subjects (humans and rodents) learn to associate the rewarding properties of Meth with particular contextual cues. After the association develops subjects will choose to spend more …

    loyola-thes Repository record

  13. mGluR5 Involvement in Methamphetamine Reward and the Co-Morbidity of Schizophrenia and Stimulant Use Disorders

    Herrold, Amy Anne2013

    … in the laboratory with humans and rodents using conditioned place preference (CPP). In the laboratory, repeated Meth administration also produces a progressive enhancement in motor activity termed motor sensitization. It is hypothesized that the neuronal adaptations associated with motor …

    loyola-thes Repository record

  14. Investigations of the neurobiological and behavioural actions of cocaine

    Brown, Erin E.University of British Columbia1993

    … cocaine and buprenorphine were examined using a conditioned place preference (CPP) procedure and in vivo microdialysis. Cocaine and buprenorphine both elicited CPP; moreover, these drugs interacted to produce significantly larger CPPs when given in combination. Both cocaine and buprenorphine …

    ubc Repository record

  15. Chronic Stress during Adolescence Alters Alcohol-Induced Conditioned Place Preference in Mice Selectively Bred for High Alcohol Preference but no Low Alcohol Preference

    Breit, Kristen R

    … days after stress exposure, all subjects began a conditioned place preference (CPP) paradigm, a behavioral task that measures the sensitivity to alcohol's rewarding effects. Since re-exposure to a stressor has been associated with an increased risk in relapse and other drug-seeking behaviors, half …

    purdue-thes Repository record

  16. Mass spectrometry-based identification and quantitation of endogenous peptides in complex biological matrices

    Dowd, Sarah EUniversity of Illinois at Urbana-Champaign2016

    … and amygdala of mice to study the extinction of conditioned place preference (CPP) for cocaine in mice that have access to a running wheel after CPP training. MS measurements have yielded both known and novel candidate peptides that show relative abundance changes with exercise and context …

    uiuc Repository record

  17. Meccanismo d'azione del Pramipexolo nella terapia della malattia di Parkinson

    ESPA, ELENAUniversità degli Studi di Cagliari2015

    … or in combination with levodopa as Dopamine Replacement Therapy in Parkinson’s disease. In clinical and preclinical studies, PPX improved motor deficits, this evidence led to lowering daily dose of levodopa, delaying the motor side effects associated with its use. Recently, PPX administration …

    cagliari Repository record

  18. The effect of voluntary binge caffeine and ethanol coexposure on neurobehavioral sensitivity to cocaine in male C57BL/6J mice

    Fritz, Brandon M

    … underwent an identical drinking procedure. A conditioned place preference (CPP) protocol commenced on day 15. CPP assesses the conditioned rewarding effects of cues associated with drugs of abuse. On day 15, mice received saline injections and were immediately placed onto a neutral floor …

    purdue-thes Repository record

  19. The effect of voluntary binge caffeine and ethanol co-exposure on neurobehavioral sensitivity to cocaine in male C57BL/6J mice

    Fritz, Brandon M.2016

    … underwent an identical drinking procedure. A conditioned place preference (CPP) protocol commenced on day 15. CPP assesses the conditioned rewarding effects of cues associated with drugs of abuse. On day 15, mice received saline injections and were immediately placed onto a neutral floor …

    iupui Repository record

  20. Fragmented maternal care programs altered pain vulnerability and aberrant responses to opioids

    Sneddon, Claire CampbellUniversity of Dundee2020

    … techniques such as the tail withdrawal assay, conditioned place preference (CPP), and locomotor analysis. We also investigated the influence of FC on the expression and methylation of key genes including those encoding opioid peptide precursors, MOP, DOP, Barr2 and c-Src in several brain …

    dundee Repository record

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