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Showing 1 to 1 of 1 for “"Conditional cre/lox knock out"”.
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Aspects of T cell development contributing to autoimmunity.
… was dissected by using TGF-β type II receptor cre/lox conditional knock out mouse model. By transplanting bone marrow to irradiated recipients we restricted the phenotype to hematopoietic stem cells. These mice develop a lymphoproliferative degenerating disease 6 to 9 weeks after bone marrow …