Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 419 for “"Computational tools."”.
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Computational tools for assembly oriented design
Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1999.
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Computational tools for enabling longitudinal skin image analysis
We present a set of computational tools that enable quantitative analysis of longitudinally acquired skin images: the assessment and characterization of the evolution of skin features over time. A framework for time-lapsed skin imaging is proposed. A nonrigid registration algorithm based on …
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Computational tools for including specificity in protein design
Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2002.
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Computational tools for modeling and measuring chromosome structure
… impossible. This thesis contributes two computational projects to these efforts. The first project is a set of online and offline calculators of conformational statistics using a variety of published and unpublished methods, addressing the current lack of DNA model-building tools intended …
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Assembly oriented design : concepts algorithms and computational tools
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1998.
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Computational Tools for Chemical Data Assimilation with CMAQ
… These experiments further validate the tools developed in this thesis.
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Computational Tools for Molecular Networks in Biological Systems
Theoretical molecular biologists try to understand the workings of cells through mathematics. Some theoreticians use systems of ordinary differential equations (ODEs) as the basis for mathematical modelling of molecular networks. This thesis develops algorithms for estimating molecular reaction …
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Genetic and Computational Tools for Engineering Complex Prokaryotic Systems
Prokaryotic systems are promising platforms for bioproduction, but the complexity of their gene regulatory and metabolic networks presents significant challenges for engineering efficient biosynthetic pathways. While CRISPR-Cas technologies have revolutionized genome editing in eukaryotes, the …
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Computational Tools for 3D Printing and Woven Textile Design
… advantages. These novel techniques call for new tools to aid design and new algorithms to process the input and generate machine instructions for fabrication. This dissertation includes three works on computational tools for wireframe printing and 3D weaving. In the first work, we present a …
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Computational tools for monitoring neural connectivity using calcium imaging
The development of optogenetics and calcium imaging have enabled light-activated manipulation and monitoring of neural activity that offer powerful alternatives to traditional electronic and chemical methods. Along with light-evoked activity, many technical advancements have been made that allow …
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Development and application of computational tools for metabolic engineering
Modeling and computational tools are proven to be extremely successful in streamlining the design and engineering of different systems in many areas of science and engineering. However, due to its complex nature, modeling in biology is in an early stage and many more years of development is …
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Computational Tools for Metabolic Modeling and Gene Duplication Analysis
This thesis presents new computational methods to analyse both short and long-term effects of temperature increase on biological systems. First, we consider the problem of acclimation of an organism to increased temperatures on short timescales. We develop a novel method of network regression, …
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Computational Tools for Annotating Antibiotic Resistance in Metagenomic Data
… of short sequencing reads that are processed by computational tools. However, with the rapid adoption of metagenomics a large amount of data has been generated. This situation requires the development of computational tools and pipelines to manage the data scalability, accessibility, and …
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Computational Tools and Analyses for Improved Inference of Variant Effects
… variants in selected protein targets, while computational methods seek to infer missense variant impacts using statistical modelling. Here I describe work to assist and exploit both MAVE and computational studies.To assist in planning and to promote collaboration and efficient communication …
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Development of Computational Tools and Resources for Cotton microRNA Analysis
… been subsequentially identified in cotton by computational prediction or small RNA sequencing, many of which were also shown to be expressed differentially during fiber development. However, although miRNA-related research has become one of the hottest research in biology in the past decade …
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Narration of light : computational tools for framing the tonal imagination
… And images depict them. This thesis proposes a computational model for evaluating tonal and compositional qualities of photorealistically rendered synthetic images. Its aim is to assist the architects to quickly externalize their spatial imagination through automated evaluation and selection of …
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Towards Digital Liminality : computational tools for 'beyond average' creative thinking
… as machine learning are increasingly employed in tools used in the early phases of the design process. These computational techniques undeniably surpass humans at quickly generating numerous designs and calculating 'optimised' responses, but their average-driven approaches are limited when it …
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Development of computational tools to model molecular interactions for medicinal chemistry
… over the past 40 years to rely heavily on the computationally aided design of new drugs. The work in this dissertation focuses on developing computational tools for the application of medicinal chemistry. For computational techniques to be dependable, important interactions must be properly …
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Development of Instrumental and Computational tools for investigation of polymer flammability
This thesis describes published work undertaken over the last 17 years. The main focus is the development and utilization of the microscale combustion calorimeter (MCC) and how it helps us understand the flammability of materials. A reproducible way to quantitatively assess material flammability …
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