Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"Computational dissection"”.
-
Computational dissection of nitrate transport mechanism
… major focuses of this thesis. First, we develop computational algorithms to enhance the efficiency and accuracy of MD simulations. We leverage coevolutionary relationships conserved in protein sequences to predict the slow dynamical changes of proteins, which can be used to guide MD sampling of …
-
Computational dissection and prediction of cancer immunotherapy response
Checkpoint blockade immunotherapies have transformed the standard of care and outcomes for many cancer types; however. more than 60% of patients still do not experience a durable clinical response from these treatments. To address this problem, the development of novel biomarkers and more effective …
-
Computational Dissection of Composite Molecular Signatures and Transcriptional Modules
… to analyze gene expression profiling data for computational dissection of molecular signatures and transcriptional modules. The first part of the dissertation is focused on extracting pure gene expression signals from tissue or cell mixtures. The main goal of gene expression profiling is to …
-
Coupled theoretical and experimental methods to characterize heterogeneous, anisotropic, nonlinear materials: application to cardiovascular tissues
… and preferred orientation. It allows for the computational dissection of samples, capturing regional differences within a single sample nondestructively. However, the linear assumption implicit in GAIM limited its utility, particularly in the case of cardiovascular soft tissues, which exhibit …