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Showing 1 to 1 of 1 for “"Computational Biology, Glutamate Dehydrogenase"”.
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Thermodynamics of Ligand Binding to Glutamate Dehydrogenase
The role of glutamate dehydrogenase (GDH) in disease has been exhibited in congenital hyperinsulinism, specifically, hyperinsulinism/hyperammonemia syndrome (HHS). GDH catalyzes the reversible deamination of glutamate to 2-oxoglutarate. Mutations in GDH can lead to GDH over activity, causing …