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Showing 1 to 4 of 4 for “"CompuCell3D"”.
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Mathematical Modelling of Cancer Growth and Development: Adhesion, Stem Cells and Structure
… model created with the software package CompuCell3D. This was compared to a novel continuum model, which can be used to perform in silico experiments of solid tumours with a stem-progenitor-mature cell structure for a biologically relevant number of cells. Lastly, a cell-based model of a …
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Mathematical Modelling of the Immune Response to Cancer
… using the computational simulation plat- form, CompuCell3D, to extend an earlier spatio-temporal model of tumour dormancy (Matzavinos et al. [2004]). Chapter three investigates and analyses an ODE model of the interaction of two immune cells and two tumour cells. This model is extended to …
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Mathematical modelling of cancer cell invasion of tissue: discrete and continuum approaches to studying the central role of adhesion
Adhesion, which includes cell-to-cell and cell-to-extracellular-matrix adhesion, plays an important role in cancer invasion and metastasis. After undergoing morphological changes malignant and invasive tumour cells, i.e., cancer cells, break away from the primary tumour by loss of cell-cell …
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Clonal Dynamics in Barrett's Oesophagus and Oesophageal Adenocarcinoma
… and morphology development was built using CompuCell3D. LOH progression was assessed using whole genome sequencing on a cohort of 100 pre-OAC samples, encompassing IM, dysplasia, and IMC, as well as a cohort of 81 pairs of BO (IM and dysplasia) and OAC samples. Intra-tumour heterogeneity and …