Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Complex Genomic Rearrangements"”.
-
Decoding Copy Number Substructure and Evolution From Single Cell Genomics
… in which tumors undergo a period of elevated genomic instability, acquiring complex genomic rearrangements within a short timeframe followed by clonal stasis. However, these observations rely on limited cell numbers and inherent experimental bias from first-generation single cell technologies. …
-
Reconstructing Mutational Lineages In Breast Cancer By Multi-Patient-Targeted Single Cell Dna Sequencing
… of breast cancer patients and is indicative of complex genomic rearrangements that are acquired during tumor initiation. Although copy number aberrations have been extensively studied in relation to aneuploidy and TNBC initiation, little is currently known regarding the timing and impact of …
-
Identifying the Genetic Factors in Natural Genome Backgrounds That May Modulate Phenotypic Outcomes in C. elegans
… including Single Nucleotide Variants (SNVs) and complex Structural Variants (SVs) such as deletions, duplications, inversions, as well as complex genomic rearrangements that may act as potential genetic modifiers. This study is the first to explore the SV category in natural isolates of C. …