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Showing 1 to 1 of 1 for “"Complement System Proteins"”.
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Potentiating Antibody Therapy by Targeting Complement on Cancer Cells
… these escape variants carried covalently bound complement activation fragments, especially C3d. Indeed, C3d opsonized CLL cells persisted for weeks in circulation. (Beurskens et al., 2012). At final restaging after combined ofatumumab and chemotherapy treatment, many patients had CD20 negative, …