Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Competitive assays"”.
-
Synthesis and Structure-Activity Relationship Studies of 3-(N-Butylethanimidoyl)-4-hydroxy-2H-chromen-2-one (BHC) Analogues for Myosin II Inhibition
… of the analogues determined through ATPase assays found the trend that both longer linear alkyl and methyl-aromatic imino tails are favored. The lead analogues tested containing a hexyl and a benzyl imino tail have a IC50 values of 1.2 ± 1.0 µM and 0.8 ± 0.2 µM, respectively, to skeletal …
-
Structural basis for the function of the transcriptional regulator KstR from Mycobacterium tuberculosis
… quenching assay). Protein-DNA binding assays have demonstrated that the 21-amino-acid extension at the N-terminus of KstR imposes a positive but non-essential role for KstR-DNA interaction. Protein-ligand binding assays and competitive assays (of protein, DNA and ligand) have been used …
-
Optimization and Applications of Fluorescence anisotropy assays and Fluorescence Resonance Energy Transfer Measurements
… and negatively charged dyes. Secondly, FA based assays for direct determination of affinities of CaM-target interactions are developed and the results are consistent with previously reported values. Finally, a FRET based methods are used to study the mechanism of activation of PMCA by CaM and …