Global ETD Search

Tirosine Kinase Receptors expression in canine mammary tumours and in vitro and in vivo evaluation of Tirosine Kinases inhibitors biological activity. Evaluation of possible molecular targets in comparative oncology

De Maria, Raffaella, Gattino, FrancescaUniversità degli Studi di Torino2018

unito Repository record for Tirosine Kinase Receptors expression in canine mammary tumours and in vitro and in vivo evaluation of Tirosine Kinases inhibitors biological activity. Evaluation of possible molecular targets in comparative oncology (opens in a new tab)

ASSESSMENT OF RELEVANT MOLECULAR TARGETS WITH THERAPEUTIC SIGNIFICANCE IN CANINE NEOPLASMS.

DELL'AERE, SILVIAUniversità degli Studi di Milano2026

… position canine cancers as valuable models for comparative oncology and translational research. Increasing canine life expectancy and advances in diagnostics have highlighted the need for effective, targeted therapies. While targeted therapies such as tyrosine kinase inhibitors, monoclonal …

milano Repository record for ASSESSMENT OF RELEVANT MOLECULAR TARGETS WITH THERAPEUTIC SIGNIFICANCE IN CANINE NEOPLASMS. (opens in a new tab)

BMP Signaling Regulates Germ Cell Pluripotency, Sexual Differentiation, and Cancer Susceptibility

Sanchez, Angelica2019

… sequencing analysis in a cross-species comparative oncology approach to identify genes and pathways with fundamental importance to the development of the human disease. I further defined the role of specific BMP ligands in mediating germ cell differentiation and identified reciprocal …

utswmed Repository record for BMP Signaling Regulates Germ Cell Pluripotency, Sexual Differentiation, and Cancer Susceptibility (opens in a new tab)

Identifying the basis for anticancer synergy with PAC-1, with applications to meningioma

Tonogai, Emily J.University of Illinois at Urbana-Champaign2022

Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01

uiuc Repository record for Identifying the basis for anticancer synergy with PAC-1, with applications to meningioma (opens in a new tab)

Molecular basis of immunotolerance in canine neoplasia

Stevenson Salinas, Valentina BeatrizVirginia Tech2023

Melanoma is a highly malignant neoplasia with high rates of metastasis in humans and dogs. Regardless of being considered a highly immunogenic neoplasm, the function of the immune system is hampered by the expression of immune checkpoint molecules by the cancer cells. In contrast, soft tissue …

vt Repository record for Molecular basis of immunotolerance in canine neoplasia (opens in a new tab)

Improving Nk Cell Therapy For Osteosarcoma

Foltz, Jennifer, <p>0000-0001-9158-3464</p>2019

<p>Osteosarcoma (OS) is the most common primary bone tumor. Despite new treatment options, 5-year survival for metastatic OS has remained at only 30% for the last 30 years. Adoptive transfer of Natural Killer (NK) cells holds promise for a new, non-toxic therapy for OS. NK cells are part of the …

uthsc Repository record for Improving Nk Cell Therapy For Osteosarcoma (opens in a new tab)

Preclinical Models to Identify Molecular Drivers of Metastasis in Paediatric Musculoskeletal Cancer

Palmer, CharlotteUniversity of Cambridge2020

Paediatric primary musculoskeletal (MS) cancers such as Ewing’s sarcoma and osteosarcoma account for 5% of childhood malignancies in the UK. Despite advances in surgical intervention and chemotherapy, the survival of patients with these malignancies has not improved substantially over the last 20 …

cambridge Repository record for Preclinical Models to Identify Molecular Drivers of Metastasis in Paediatric Musculoskeletal Cancer (opens in a new tab)