Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 1 of 1 for “"Combinatorial CRISPR screening"”.
-
Determining therapeutically actionable genetic interactions in human cancer at scale using multiplexed CRISPR screening
… study employed a high-throughput multiplexed combinatorial CRISPR/Cas9 pooled screening approach to systematically identify SL interactions. A novel tRNA-based dual guide expression system was used to construct the Synergy library, enabling comprehensive and unbiased monogenic and digenic …