Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Combination regimens"”.
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Utilization of Model-Based Approaches to Maximize Efficacy of Antibiotics for the Treatment of Mycobacterium abscessus Pulmonary Infection
… generally more than 12 months with a multidrug combination of at least four agents. However, no optimal combination, regimen, or treatment duration has been universally established for Mab pulmonary infections (Mab-PI). Therefore, the selective and strategic use of the most potent agents …
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The efficacy and safety of artesunate suppositories in combination with other antimalarials in the treatment of severe malaria in Sudan.
… rates of 100%, 100% and 96.7% respectively. The combination with either doxycycline or pynmethamine/sulphadoxine is equally effective to that followed by mefloquine in preventing recrudescence. The three combination regimens provided a radical cure rate 100% that is significantly higher than …
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Targeting Histone Deacetylases (Hdac) For The Treatment of Soft Tissue Sarcoma
… efficacy of HDACi as monotherapy and in combination with chemotherapy in a panel of genetically complex STS. We found that HDACi combined with chemotherapy significantly induced anti-STS effects <em>in vitro</em> and <em>in vivo</em>. We then focused our study of HDACi in malignant …
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Prevalence and incidence of hypertension and diabetes mellitus in HIV infected persons on HAART in Chongwe district in Lusaka province.
… determinants T2DM and hypertension show that ART combination (p=0.001), age category (p=0.011) and cigarette smoking (p=0.0460) significantly added to the prediction model for T2DM outcome; and that ART combination (p=0.004), sex (p=0.001), family history of hypertension (p=0.007) and cigarette …
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Prevalence and incidence of hypertension and diabetes mellitus in HIV infected persons on HAART in Chongwe district in Lusaka province.
… determinants T2DM and hypertension show that ART combination (p=0.001), age category (p=0.011) and cigarette smoking (p=0.0460) significantly added to the prediction model for T2DM outcome; and that ART combination (p=0.004), sex (p=0.001), family history of hypertension (p=0.007) and cigarette …
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PKPD-Model Based Preclinical Characterization of the Activity of Spectinamide 1599 Against Mycobacterial Subpopulations. and the Identification of Potential Partners for Combination Therapy
… screen and characterize ternary drug combinations containing spectinamide 1599 in BALB/c mouse models of TB. The metanalysis process involved building models to describe natural growth of mycobacteria in the lungs of mice, the PK/PD effect of single and binary anti-TB drug regimens on …