Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Column switching"”.
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A study of column switching liquid chromatography in drug analysis.
… of biological fluids are reviewed. A survey of column switching liquid chromatography techniques revealed the range of column dimensions, the frequency of prior sample pretreatment steps and small injection volumes used and the varied longevity of the columns. The advantages and disadvantages of …
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Extraction and analysis of pharmaceutical residues in environmental samples using SPE with LC-MS/MS
… balanced polymeric phases or the use of column switching, whereby short reversed-phase monolithic micro-columns were applied as suitable traps for on-line preconcentration. Method performance data for all the developed methods were also determined and analytical detection limits were …
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On-line liquid distribution chromatographic/spectrofluorometric determination of PAH distribution in coal-derived products
… The PAHs were isolated by preparative silica gel columns with a hexane mobile phase, and fractionated into five samples based on the number of condensed rings. Each fraction was separated by reverse phase HPLC with an acetonitrile/water mobile phase. Compounds were detected by means of on-line …
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Studies of UHPLC-MS performance and application to rapid sensitive and robust drug analysis
… matrix effects and sensitivity. Finally, a switching system comprising two different, complementary stationary phase materials is designed and evaluated to widen the elution window, allowing for the simultaneous analysis of both polar and non-polar analytes.<br/>A combination of Hypercarb …
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Development of novel extraction and separation methods for the determination of anthracyclines and taxanes simultaneously from biological matrices
… separation and detection was achieved on-line by column-switching between an SPE column and an analytical column. The optimum type of switching valve, extraction conditions and separating conditions were evaluated for both methods in order to obtain the highest recovery possible for each target …
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Schnelles und zuverlässiges therapeutisches Drug-Monitoring mit HPLC-UV und LC/LC-MS/MS aus komplexen Matrizes
Voraussetzung für das therapeutische Drug-Monitoring ist, dass die analytische Methode schnell qualitativ hochwertige Ergebnisse liefert. Ausgehend von diesen Kriterien wurden Nachweismethoden für Antimykotika und Antibiotika entwickelt und sowohl in klinischer Routine als auch in klinischer …
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Studies in ion exchange chromatography
… 100,000 ppm sulfate. A standard anion exchange column will completely lose resolution between chloride and sulfate at a sulfate concentration of approximately 2500 ppm. The apparatus designed and built by the author uses two analytical ion—exchange columns coupled in series by a high pressure …