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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 537 for “"Colorectal Cancer"”.

  1. Obesity Induced Colorectal Cancer

    Ford, MauntellThe Ohio State University2013

    … in the world are overweight or obese [32]. Colorectal cancer takes the lives of 608,000 people each year[32]. It is important to study the negative impact of obesity on the body and population and the etiology of colorectal cancer. My goal was to create a mathematical model that relates …

    ohiolink Repository record

  2. Familial colorectal cancer 2.0. Implementation of guidelines on familial and hereditary colorectal cancer

    Dekker, N.[S.l.] : [S.n.]2013

    Contains fulltext : 118430.pdf (Publisher’s version ) (Open Access)

    radboud Repository record

  3. Microbiome Analysis in Colorectal Cancer

    Dadkhah, Ezzat2017

    gmu

  4. MUC13 Enhances Colorectal Cancer Metastasis

    Doxtater, Kyle2022

    <p>Colorectal cancer (CRC) is one of the most prevalent cancer worldwide with a 5% lifetime incidence in developed countries. It is third most common cause of cancer related death in the United States and the second deadliest when men and women are combined. Encouragingly due to changes in dietary …

    tenn-hsc Repository record

  5. Multimodality imaging in colorectal cancer

    Heijmen, L.S.l. : s.n2014

    Contains fulltext : 132069.pdf (Publisher’s version ) (Open Access)

    radboud Repository record

  6. Metabolomic Biomarkers for Colorectal Cancer

    Farshidfar, FarshadGraduate Studies2016

    Colorectal cancer (CRC) is the second most common cancer in the North America. It is also a huge burden for society. Remarkable efforts have been and are being made to improve CRC diagnosis, to enhance the effectiveness of treatments, and to eventually improve the outcome of these patients. …

    calgary Repository record

  7. Genomic instability in sporadic colorectal cancer

    Curtis, Lucy JaneThe University of Edinburgh1998

    edinburgh Repository record

  8. Beta-catenin Complexes in Colorectal Cancer

    Mackay, Craig DonaldUniversity of Dundee2015

    … that initiate and drive the progression of colorectal cancer cause defects in key signalling pathways that affect cell function. The Wnt signalling pathway is a key pathway that is disrupted in colorectal cancer and β-catenin is the key mediator of Wnt signalling. β-catenin is a …

    dundee Repository record

  9. MICRORNAS AND THE DEVELOPMENT OF COLORECTAL CANCER

    Chen, Li

    mtu Repository record

  10. Impact of Diabetes on Colorectal Cancer Outcomes

    Shah, Neel A.2019

    Diabetes is one of the most common chronic comorbid condition seen in elderly CRC patients. Outcomes of CRC patients with diabetes specifically stage at diagnosis, emergency condition for CRC surgery, survival, and mortality have been insufficiently explored. The aims of the study were to …

    wvu Repository record

  11. Colorectal Cancer Screening: A Non-Invasive Approach

    Frazier, Amy Beckman

    <p>COLORECTAL CANCER SCREENING: A NON-INVASIVE APPROACH Amy Frazier May, 2004 58 Pages Directed by: Dr. Donna Blackburn, Dr. Patricia Bailey, and Dr. Thomas Nicholson Department of Nursing Western Kentucky University Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide and …

    wku-diss Repository record

  12. Nherf1 – New Modifier of Colorectal Cancer Progression

    Hayashi, Yuho2010

    Colorectal cancer (CRC) develops from multiple progressive modifications of normal intestinal epithelium into adenocarcinoma. Loss of cell polarity has been implicated as an early event in this process, but the molecular players involved are not well known. NHERF1 (Na+/H+ Exchanger Regulatory …

    uthsc Repository record

  13. Quality aspects of Dutch colorectal cancer trials

    Mol, L.S.l. : s.n.2017

    Contains fulltext : 173476.pdf (Publisher’s version ) (Open Access)

    radboud Repository record

  14. Targeting gold nanoparticles constructs in colorectal cancer

    Patel, N.Middlesex University2020

    middlesex Repository record

  15. Role of ATRX in colorectal cancer metastasis

    Peckett, NatThe University of Edinburgh2025

    … repair. ATRX is frequently mutated in many cancer types and in colorectal cancer (CRC) loss of ATRX is associated with the CRIS-B subtype, poor prognosis, and late stage and metastatic disease. There are currently few therapeutic options for patients with metastatic disease and accordingly, …

    edinburgh Repository record

  16. The chromatin landscape of colorectal cancer cells

    Magagula, Loretta QinisileDivision of Chemical and Systems Biology2020

    … dynamics and transcriptional activity. With cancer increasingly becoming the greatest health epidemic of our time, the comprehensive genomic characterization of tumor genotypes has become central to current therapeutic approaches. Functioning as the basic unit of chromatin organisation, …

    cape-town Repository record

  17. DISSECTING RESISTANCE TO IMMUNOTHERAPY IN MSS COLORECTAL CANCER

    SCARDELLATO, SHARONUniversità degli Studi di Milano2024

    Patients with colorectal cancer (CRC) exhibiting DNA mismatch repair deficiency and microsatellite instability (MSI) often display favorable responses to immune checkpoint inhibitor (ICI) therapies, in contrast to mismatch repair proficient and microsatellite stable (MSS) tumors. While the high …

    milano Repository record

  18. Modulation of Pi3K-Akt Pathway In Colorectal Cancer

    Nusrat, Maliha, <p>https://orcid.org/0000-0002-0417-0416</p>2021

    … (PI3K) signaling pathway is activated in 20-40% colorectal cancers (CRC) through PTEN loss (PTEN<sup>loss</sup>) and <em>PIK3CA</em> mutations (<em>PIK3CA</em><sup>mut</sup>). Allosteric AKT inhibition with MK2206 monotherapy has been ineffective in CRC patients. We investigated the impact of …

    uthsc Repository record

  19. Telomeric Regulation of Chromosomal Instability In Colorectal Cancer

    LaBella, Kyle, A LaBella, Kyle, <p>0000-0002-0473-9262</p>2024

    … While CIN provides a mutator mechanism for cancer-relevant genomic events, its role in shaping tumor biology during carcinogenesis is not well understood. Here, we explored the molecular and biological impact of telomere dysfunction and associated CIN <em>in vivo</em> in a faithful model of …

    uthsc Repository record

  20. Epigenetic Modulation In Braf Mutated Metastatic Colorectal Cancer

    Morris, Van2016

    … clinical outcomes for patients with metastatic colorectal cancer (mCRC). Unlike other tumors with the same mutation, BRAF inhibitors are ineffective as monotherapy. CRC tumors with BRAF V600E mutations are associated with global hypermethylation, which may turn off tumor suppressor gene …

    uthsc Repository record

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