Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 720 for “"Colorectal"”.
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Obesity Induced Colorectal Cancer
… in the world are overweight or obese [32]. Colorectal cancer takes the lives of 608,000 people each year[32]. It is important to study the negative impact of obesity on the body and population and the etiology of colorectal cancer. My goal was to create a mathematical model that relates …
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Familial colorectal cancer 2.0. Implementation of guidelines on familial and hereditary colorectal cancer
Contains fulltext : 118430.pdf (Publisher’s version ) (Open Access)
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MUC13 Enhances Colorectal Cancer Metastasis
<p>Colorectal cancer (CRC) is one of the most prevalent cancer worldwide with a 5% lifetime incidence in developed countries. It is third most common cause of cancer related death in the United States and the second deadliest when men and women are combined. Encouragingly due to changes in dietary …
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Multimodality imaging in colorectal cancer
Contains fulltext : 132069.pdf (Publisher’s version ) (Open Access)
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Metabolomic Biomarkers for Colorectal Cancer
Colorectal cancer (CRC) is the second most common cancer in the North America. It is also a huge burden for society. Remarkable efforts have been and are being made to improve CRC diagnosis, to enhance the effectiveness of treatments, and to eventually improve the outcome of these patients. …
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MiRNA-Mediated Regulation of Colorectal Tumorigenesis
<p>Colorectal cancer (CRC) is the third most commonly diagnosed malignancy in the United States and a leading cause of cancer morbidity. The initiation and progression of colorectal tumorigenesis is characterized by the accumulation of genetic alterations that allow for uncontrolled gene expression …
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Beta-catenin Complexes in Colorectal Cancer
… that initiate and drive the progression of colorectal cancer cause defects in key signalling pathways that affect cell function. The Wnt signalling pathway is a key pathway that is disrupted in colorectal cancer and β-catenin is the key mediator of Wnt signalling. β-catenin is a …
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Impact of Diabetes on Colorectal Cancer Outcomes
Diabetes is one of the most common chronic comorbid condition seen in elderly CRC patients. Outcomes of CRC patients with diabetes specifically stage at diagnosis, emergency condition for CRC surgery, survival, and mortality have been insufficiently explored. The aims of the study were to …
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Colorectal Cancer Screening: A Non-Invasive Approach
<p>COLORECTAL CANCER SCREENING: A NON-INVASIVE APPROACH Amy Frazier May, 2004 58 Pages Directed by: Dr. Donna Blackburn, Dr. Patricia Bailey, and Dr. Thomas Nicholson Department of Nursing Western Kentucky University Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide and …
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Genomic and Transcriptomic Landscape of Colorectal Premalignancy
<p>Colorectal cancer (CRC) is the third most commonly diagnosed cancer among men and women in the United States, with 3 to 5 percent of the cases diagnosed in the background of a hereditary form of the disease. Biologically, CRC is divided into two groups: microsatellite instable (MSI) and …
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Nherf1 – New Modifier of Colorectal Cancer Progression
Colorectal cancer (CRC) develops from multiple progressive modifications of normal intestinal epithelium into adenocarcinoma. Loss of cell polarity has been implicated as an early event in this process, but the molecular players involved are not well known. NHERF1 (Na+/H+ Exchanger Regulatory …
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Quality aspects of Dutch colorectal cancer trials
Contains fulltext : 173476.pdf (Publisher’s version ) (Open Access)
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Role of ATRX in colorectal cancer metastasis
… frequently mutated in many cancer types and in colorectal cancer (CRC) loss of ATRX is associated with the CRIS-B subtype, poor prognosis, and late stage and metastatic disease. There are currently few therapeutic options for patients with metastatic disease and accordingly, very high mortality …
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Surguvant inflammation and metabolism in colorectal surgery
… 3. Explore the perioperative metabolome in colorectal surgery 4. Investigate the effect of ‘surguvant’ systemic anti-inflammatory therapy on the perioperative metabolome in colorectal cancer surgery Methods: The association between CT-generated BCPs and five-year cancer recurrence and …
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Prehabilitation for Enhanced Recovery After Colorectal Surgery
… preoperative status modifies outcomes in colorectal surgery. Results: First, intermediately frail and frail patients with poor functional walking capacity before surgery suffer more postoperative complications than patients with better functional walking capacity. Second, nutrition …
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