Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Colonization resistance"”.
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Factors Governing Gastrointestinal Colonization of Candida albicans
… by which gut microbiota mediate C. albicans colonization resistance in the gut, however, are unknown. Here, we show that gut microbiota-derived short chain fatty acids (SCFA) directly inhibit C. albicans growth in vitro. SCFA inhibit C. albicans hexose uptake and induce intracellular …
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Predicting Colonization of Microbes in the Human Gut
… emergent phenotype by these microbes is colonization resistance, the process by which a microbial community resists colonization of an exogenous microbe. This resistance barrier is critical for protecting humans from infectious enteric pathogens. However, it is detrimental to the …
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Towards in vivo editing of the human microbiome
… microbiota face several challenges, including colonization resistance in competitive environments such as the gut, and imprecise ecological perturbations using antibiotics and fecal transplants. The fundamental objective of this research is to develop safe methods to genetically edit the …
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The Effects Of The Estrus Cycle On Microbiota Composition And The Opportunistic Pathogen Listeria Monocytogenes Infection Process In Murine Models
… rate. Infection in healthy individuals causes colonization of the intestinal lumen and subclinical noninvasive listeriosis. However, translocation of L. monocytogenes across the intestinal epithelium produces invasive systemic listeriosis with central nervous system involvement. Little is known …
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Control of Salmonella Virulence by Microbiota-Derived and Dietary Fatty Acids
… virulence of invading pathogens, providing colonization resistance to the host. In some cases, pathogens could exploit these metabolites as environmental signals to enhance its survival and expansion. These findings highlight the importance of understanding the intricate interactions between …
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Effects of prebiotic fibre diets on rat mucosal intestinal and systemic immunity and in vitro mechanistic analysis of anti-inflammatory effects of lactobacillus strains on rat and human intestinal epithelial cells
… acids, maintaining bowel function, building colonization resistance (against pathogens) and treating antibiotic-associated diarrhea as well as colitis. Although both probiotic and prebiotic effects on immune system have been studied, the mechanisms of their activity are still not clearly …