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Showing 1 to 2 of 2 for “"Colloidal Drug Aggregates"”.
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Controlling the Stability of Colloidal Drug Aggregates for Chemotherapeutic Delivery
Colloidal aggregation presents a significant nuisance in drug discovery programs; the self-assembly of hydrophobic compounds into colloidal particles leads to numerous artifactual results in screening assays. In biochemical enzyme inhibition assays colloids non-specifically adsorb proteins leading …
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Drug delivery strategies to overcome ocular hypertension
… limitations, this thesis explores two innovative drug delivery strategies using anti-glaucoma drug-rich nanoparticles, called colloidal drug aggregates (CDAs). The first strategy involves a periocular hydrogel-nanoparticle composite designed for sustained, local delivery to the eye. Timolol …