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Showing 1 to 1 of 1 for “"Collateral lethality"”.

  1. The Tca Cycle As A Nexus of Metabolic Vulnerabilities In Cancer

    <p>Uncontrolled proliferation of cancer cells necessitates rewiring of metabolic pathways to meet biosynthetic and bioenergetic demands of proliferation and fortify redox homeostasis. An increasing body of literature suggests that mitochondrial metabolism (tricarboxylic acid cycle (TCA) and …

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