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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"Collagen-Based"”.
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Assessment of collagen based polymer scaffolds for tissue engineering
The use of collagen-glycosaminoglycan copolymers in tissue engineering scaffolds has seen promise to date in skin regeneration templates, hollow nerve guides for peripheral nerve regeneration, and conjunctiva regeneration. Future applications appear to be directed toward both in vivo and in vitro …
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Mechanical properties of collagen-based scaffolds for tissue regeneration
Collagen-glycosaminoglycan (CG) scaffolds for the regeneration of skin and nerve have previously been fabricated by freeze-drying a slurry containing a co-precipitate of collagen and glycosaminoglycan. Recently, mineralized collagen-glycosaminoglycan (MCG) scaffolds for bone regeneration have been …
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A collagen based scaffold for the repair of annulus fibrosus defects
… was to evaluate the regenerative potential of a collagen type II scaffold on standardized defects of the AF. Specifically, this thesis evaluated in vitro the effects of the culture conditions, of a select group of growth factors, of the cross-linking method and of the biochemical composition of …
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Development of collagen-based scaffolds for differentiation of induced pluripotent stem cells
<p>Collagen hydrogel has been broadly studied and applied in engineering 3D scaffold materials in tissue engineering. A collagen hydrogel can provide cells with a porous and soft environment to proliferate and differentiate. However, lacking mechanical stiffness and shrinkage resistance made it a …
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Quantifying collagen-based biological tissues using Fourier-transform-second-harmonic generation imaging
… (FT-SHG) imaging to quantify the arrangement of collagen fibers in biological tissues in 3D. Collagen is the primary structural protein in the human body. Depending on the spatial arrangement of collagen fibers, collagen-based biological tissues can have a wide range of functions and mechanical …
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Multiscale models for the degradation, damage, and failure of collagen-based soft tissues
… simulate the degradation, damage, and failure of collagen-based tissues and tissue analogs. The models build on previous work that has focused primarily on the pre-failure mechanics of tissues. Enzymatic degradation was modeled by changing the effective diameter of microscale collagen fibers over …
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Manipulating the mechanical strength and biological stability of collagen-based scaffolds for tissue engineering
Collagen, the most abundant structural protein in the body, has become the most widely used matrix for tissue engineering. Implanted collagen undergoes a constant process of remodelling, and it is the balance of collagen synthesis and its gradual breakdown by the cells of the body that will …
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Mimicking the micro-environment. Construction and evaluation of complex collagen-based scaffolds for tissue engineering
Contains fulltext : 99159.pdf (Publisher’s version ) (Open Access)
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The effects of porosity and crosslinking of a collagen based artificial skin on wound healing
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1982.
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Fabrication and evaluation of a collagen-based fiber-gel three-dimensional construct for peripheral nerve repair
… nervous tissue constructs consisting of type I collagen are fabricated into a composite biomaterial scaffold to promote contact-guided growth of neuronal and glial cultures in vitro. The growth of adult tissue on these collagen-based materials is further evaluated. These constructs are assembled …
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NOVEL NANOFIBER-BASED GRAFT FOR HEART VALVE REPLACEMENT
… tissue engineering. While processed conventional collagen-based heart valves have been used for many years, they eventually fail because of inadequate cell infiltration and insufficient replacement of graft material by tissue remodeling. To overcome the graft failure due to inadequate tissue …
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Heterogeneous Distribution and Corresponding Mechanical Significance of The Mineral Phase in Fish Scales
… can be considered as a laminated composite based on collagen fibrils arranged in a cross-plywood structure. This collagen-based composite is often partially mineralized (primarily hydroxyapatite) in the scale exterior in order to resist penetration and hence to enhance protection. Together …
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Mueller-matrix-based analysis for second-harmonic generation imaging
… of the relative structural difference in collagen-based tissues by second harmonic generation (SHG) imaging techniques involving polarization investigation. The Mueller matrix formalism demonstrates a polarization-based analysis approach for assessment of varying samples. The associated …
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Extraction and characterization of collagen from bovine hides for preparation of biodegradable films
… to derive a high-value product such as collagen. Collagen is a highly sought after protein which consists of three polypeptide chains, comprising 30% of the mammalian body’s protein, being the main component of skin, connective tissue and cartilage. The purpose of this study was to …
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COLLAGEN AND ANTIOXIDANTS FROM SEA URCHINS: WASTE VALORIZATION CHALLENGES TOWARDS REGENERATIVE MEDICINE
… that sea urchin waste contains highly valuable collagen derived from by-product tissues such as the peristomal membrane, which can be used as an innovative biomaterial for tissue engineering. The remaining part of the waste (test and spines) can be an additional source of biologically …
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Collagen implants to promote regeneration of the adult rat spinal cord
… of severed peripheral nerves through the use of collagen based implants used to bridge the resulting gap between the severed nerve stumps. The current study aims to apply this same regenerative approach to a defect created in the spinal cord of adult rats. The objective is to evaluate the …
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Detection of chemical nutrients in water using a fluidic microplasma chip with enhanced optical collection efficiency
… device and choosing an optimal concentration of collagen to fabricate microtissues. The behaviors of cells in the microtissues can be essentially the same as those of cells in a conventional cell culture system. Furthermore, this optimized microfluidic droplet device for fabricating 3D …
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Microfluidic platforms to evaluate the effects of drugs on fertility and proteins on cancer progression – a focus on cisplatin, alpha-smooth muscle actin, and glial cell line-derived neurotrophic factor
… response of cells to chemotherapy in different collagen-based hydrogels.
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