Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 53 for “"Collagen fibers"”.
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Optimizing collagen fibers for use in a collagen engine.
Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1969.
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Spinning of collagen fibers and characterizing thermal, mechanical, tensile and structural properties
Collagen is the most important building block in the entire animal world. It plays an important role in regeneration of broken bones and wound healing, also helps grow blood vessels to feed the healing areas. The use of synthetic materials has been extensive, but these materials have there own …
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Wet-spinning and thermal analysis of collagen fibers incorporating hydroxyapatite in mixed and coated form
The composition of natural bone comprises of collagen (Cg) as organic phase which acts as a matrix and inorganic calcium phosphate, particularly hydroxyapatite (HA), which is used as reinforcement. This study involved the wet-spinning of collagen fibers incorporating HA in mixed and coated form. …
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Estudo histoquímico e ultra-estrutural das fibras do sistema colágeno na glândula de veneno de Bothrops jararaca (Wied, 1824) (Reptilia, Squamata)
… with alterations in quantity and arrangement of collagen fibers. Thick collagen fibers were substituted by the fine reticular mesh in the intertubular stroma 6 hours after milking. At the 4th day of the cycle there was a rising in the number of type III fibers. Type I collagen fibers were found …
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Design and Analysis of a Collagenous Anterior Cruciate Ligament Replacement
… scaffolds comprised of reconstituted type I collagen fibers would have the potential to yield a more suitable treatment for ACL reconstruction. Ultra-violet (UV) radiation and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) were investigated as possible crosslinking methods for the …
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Quantifying collagen-based biological tissues using Fourier-transform-second-harmonic generation imaging
… (FT-SHG) imaging to quantify the arrangement of collagen fibers in biological tissues in 3D. Collagen is the primary structural protein in the human body. Depending on the spatial arrangement of collagen fibers, collagen-based biological tissues can have a wide range of functions and mechanical …
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Viscoelastic Models for Ligaments and Tendons
Collagenous tissues such as ligaments and tendons are viscoelastic materials. They exhibit a slow continuous increase in strain over time, or creep, when subjected to a constant stress and a slow continuous decrease in stress over time, or stress relaxation, when subjected to a constant strain. …
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Quantification of collagen fiber organization in biological tissues at cellular and molecular scales using second-harmonic generation imaging
Collagen is the most abundant structural protein found in the human body, and is responsible for providing structure and function to tissues. Collagen molecules organize naturally into structures called fibers on the scale of the wavelength of light and lack inversion symmetry, thus allowing for …
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Mechanical Investigation of Damage in Ligaments
… The ligament is modeled as a bundle of crimped collagen fibers that are assumed to be oriented along one direction, the physiological loading direction. The gradual straightening of collagen fibers determines the nonlinearity in the toe region of the tensile axial stress-strain curve. Straight …
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Application of beam shaping in second-harmonic generation microscopy
… of fibrillar biological structures such as collagen fibers. Quantitative analysis of SHG images has provided information about tissues, such as fibrillar organization, that can produce deeper insight into the relation between the tissue structure and its function. Further application of …
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Elastic-anisotropic properties of the porcine superflexor tendon measured by instrumented indentation
… in tendon was studied on the premise that collagen fibers in tendon are highly-ordered and unidirectional. Samples of porcine superflexor tendon were mounted for indentation such that the collagen fibers were oriented one of three possible ways relative to the indentation probe: parallel to …
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Effects of Leptin on the Rat Cervix
… capable of increasing cellular proliferation and collagen accumulation in the cervix. However, the studies conducted indicate that leptin may not modulate the extra-cellular matrix through matrix metalloproteinases, but leptin appears to play a role in the disorganization of collagen fibers.
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Nonlinear Viscoelastic Behavior of Ligaments and Tendons: Models and Experiments
… tendons. The mechanical behavior of bundles of collagen fibers which form ligaments and tendons was investigated. Axial stress-stretch data and stress relaxation data at different axial stretches were collected by testing rat tail tendon fascicles. The experimental results demonstrated, for the …
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Fabrication and evaluation of a collagen-based fiber-gel three-dimensional construct for peripheral nerve repair
… nervous tissue constructs consisting of type I collagen are fabricated into a composite biomaterial scaffold to promote contact-guided growth of neuronal and glial cultures in vitro. The growth of adult tissue on these collagen-based materials is further evaluated. These constructs are assembled …
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The Effects of Topically Applied Citric Acid on Periodontally Diseased Root Surfaces
… flat areas, 4. ridges, 5. fiber-like structures (fibers). Differences were analyzed statistically using the paired Students "t" test. SEM results indicated that acid application produced significant differences only when applied to orthodontic bicuspids and root planed periodontally diseased …
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Multiscale models for the degradation, damage, and failure of collagen-based soft tissues
… simulate the degradation, damage, and failure of collagen-based tissues and tissue analogs. The models build on previous work that has focused primarily on the pre-failure mechanics of tissues. Enzymatic degradation was modeled by changing the effective diameter of microscale collagen fibers over …
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Mechanics and Modeling of Postnatal Arterial Development in Mouse Models of Varying Elastin
… with protein quantification data for elastin and collagen. The model also predicted collagen fibers would change orientation with age. To investigate this, a new method for visualizing and quantifying collagen fiber reorientation using conventional confocal light microscopy was developed. Collagen …
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Revisão anatômica para definição do ligamento hioepiglotico
… at the hyoid bone. That ligament was formed by collagen and elastic fibers, more with collagen ones. Collagen fibers were more condensate close to the hyoid bone, while elastic fibers were more condensate near the epiglottis cartilage. lt seems to be correct that the hyoepiglottis ligament can …
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Viscoelasticity of Articular Cartilage and Ligament: Constitutive Modeling and Experiments
… the strain-rate dependent tensile stiffness of collagen fibers can also contribute to the highly rate-dependent compressive response of articular cartilage, besides the fluid-driven viscoelasticity.
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The behavior of rotator cuff tendon cells in three-dimensional culture
… are composed of parallel lines of bundles of collagen fibers and fibroblasts called fascicles and a glycoprotein, superficial zone protein (SZP), which is expressed by the gene, proteoglycan 4 (PRG4) may play a role in joint and intrafascicular lubrication. Studies have shown that a smooth …
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