Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 279 for “"Colitis"”.
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Muco-membranous colitis
Under this title I propose to consider a morbid condition, which has for its essential outward manifestation the discharge per ann um of mucus in the form of membranes, casts, tubules mac., or as a a gla.iry jelly like substance,tlong with this, which I consider the one symptom, without which a …
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Neutrophil Regulation of Colitis
… 22-producing neutrophils play a crucial role in colitis. We showed that IL-23 can promote neutrophil production of IL-17 and IL-22. IL-23 signals through its receptors and further upregulates its own receptors. Subsequently, IL-23 activates the PI3K-mTOR pathway, which mediates the expression of …
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Impact of Epa and Dha Supplementation and 15-Lox-1 Expression On Colitis and Colitis-Associated Colorectal Cancer
… disease (IBD) patients not only suffer from colitis but also from increased morbidity and mortality of colitis-associated colorectal cancer (CAC). The enzyme 15-lipoxygenase-1 (15-LOX-1) is crucial to converting omega-3 fatty acid derivatives eicosapentaenoic acid (EPA) and docosahexaenoic …
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Molecular Mechanisms of American Ginseng For the Prevention and Treatment of Colitis and Colon Cancer Associated With Colitis
<p>Ulcerative colitis (UC) is a heterogenous, chronic and relapsing inflammatory condition that has a significant impact on the quality of life. Millions of people world-wide have this disease and have an increased colon cancer risk. Despite a wide variety of causes (e.g. environmental factors, …
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Neutrophil localization during C. rodentium-induced colitis
… can result in weight loss, diarrhea, hemorrhagic colitis, dehydration and potentially death. To study enteropathogenic colonization further, a murine Citrobacter rodentium (C. rodentium) model is used in this project to understand the activity of neutrophils, often the first cell line of defense, …
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Immunological responses following surgery in ulcerative colitis
… were studied following surgery for ulcerative colitis (UC). A high prevalence of ANCA was found in UC but not in Crohn’s disease. ANCA positive UC sera were found to recognise a variety of antigens, namely lactoferrin, cathepsin G, enolase and elastase. Confocal microscopy revealed maximum …
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Tributyrin supplementation and colitis in young pigs
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-15 without embargo terms
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Evaluation of pediatric acute ulcerative colitis management protocol
<p>Pediatric patients with ulcerative colitis (UC) represent a high-risk population with severe disease that requires hospitalization. This study evaluates the impact of implementing an acute UC management protocol on 39 pediatric patients. After analysis, significant trends were shown for admitted …
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Non-Psychotropic cannabinoids attenuate visceral pain in colitis
… diseases (IBD), Crohn’s disease and ulcerative colitis, are complex chronic diseases that affect an increasing proportion of the population. Abdominal pain is a major clinical symptom, but current treatments are limited and a source of frustration for patients, many of whom seek alternatives …
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Subgrouping Ulcerative Colitis Patients using Administrative Claims Data
… in the US have been diagnosed with Ulcerative Colitis, a chronic inflammatory disease affecting the colon. Uncovering patient subgroups could improve treatment guidelines and help physicians choose an appropriate treatment plan for a patient. Here, we outline a Python implementation to generate …
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Ischemic colitis: Incidence, Risk Factors, Clinical Manifestation and Outcome
Introduction: Ischemic colitis (IC) is the most prevalent form of gastrointestinal ischemia and the second most common cause for lower gastrointestinal bleeding. The clinical course is diverse and the causes are many. Data on the incidence of IC in a population-based setting are largely lacking. …
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Colonocyte-Derived Lactate Promotes Enterobacteriaceae Fitness During Non-Infectious Colitis
… infection, antibiotics, and non-infectious colitis. We specifically probe the contribution of metabolism by members of the Enterobacteriaceae family of bacteria, a group known to commonly outgrow during intestinal inflammation. In the example of non-infectious colitis, we further explore …
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LRBA Restricts Murine Colitis by Regulating Interferon Responses and Autophagy
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Outcomes of Immune Checkpoint Inhibitor-Mediated Colitis: Multicenter Cohort Study
Immune checkpoint inhibitor (ICI)-mediated colitis (IMC) is a common and serious toxicity. Multiple reports have described the clinical presentation and course of IMC based on limited data. This was a collaborative effort from several cancer institutes to investigate features and outcomes of IMC. …
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Tissue adaptations to colitis influence neoplastic risk through clonal interaction
… described in the *Muc2<sup>KO</sup>* model of colitis, including profound remodelling of the extracellular matrix compartment pre-pathology and during active disease. Upregulation of small-leucine-rich proteoglycans was found to be an early adaptation to colitis, whilst this class of proteins …
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