Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Colistin resistance"”.
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Structure-activity relationships of niclosamide to overcome colistin resistance
Antibacterial resistance poses a significant threat to global healthcare systems, particularly against Gram-negative bacteria (GNB). Addressing this challenge requires urgent development of new therapies, especially given the emergence of resistance even to last-resort antibiotics like colistin. …
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MULTIPLEX ASSAY DESIGN
… vancomycin-resistant Enterococcus (VRE) and colistin resistance has been developed in this thesis. The resulting amplicons can be distinguished based on the principles of size, melting-state transitions, and sequence-specific probes. The problem of false-negative methicillin-resistant …
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Engineering membrane-selective antibiotic peptides to combat multidrug resistance
Antibiotic resistance is a global health emergency that mandates new drug development strategies. Natural antimicrobial peptides (AMPs) have been long-recognized as a potential source of bacteriolytic drugs, but the shortcomings of non-specific membrane toxicity, proteolytic instability, and in …
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Antimicrobial use practices and resistance in indicator bacteria in communal cattle in the Mnisi community Mpumalanga South Africa
Containing antimicrobial resistance is crucial to mitigate against a post-antimicrobial era given the current limited production of novel antimicrobial drugs. Surveillance of antimicrobial use and resistance is a critical component of antimicrobial resistance containment strategies because it …
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Measuring the abundance, diversity and overlap of Antimicrobial Resistance genes associated with humans, livestock and the environment in low- and middle-income country settings
Antimicrobial resistance (AMR) is one of the greatest threats to infectious disease management and is also challenging UN Sustainable Development Goals (UN-SDGs) in achieving health, food security and environmental well-being. Conventional AMR assessment techniques involve phenotypic …