"Colchicine derivative" · 2 results · Global ETD Search

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Showing 1 to 2 of 2 for “"Colchicine derivative"”.

Design and optimization of polymeric nanoparticles for the delivery of a novel computationally designed colchicine derivative for cancer application

RUBICONDO, MARIALUCIAPolitecnico di Torino2025

L'abstract è presente nell'allegato / the abstract is in the attachment

poli-torino Repository record for Design and optimization of polymeric nanoparticles for the delivery of a novel computationally designed colchicine derivative for cancer application (opens in a new tab)
Pharmacological investigations into matrix metalloproteinase-activated anti-tumour prodrugs. In vitro metabolic and pharmacological investigations into a series of colchicine-based peptide prodrugs activated by tumour-expressed matrix metalloproteinases

Youssef, Ahmed M.M.University of Bradford2014

… end cap. All prodrugs were conjugated to a colchicine derivative (ICT 2552) which is a vascular disrupting agent causing tumour vasculature shutdown and consequently, tumour necrosis. ICT 3146, ICT 3019, ICT 3120 and ICT 3115 prodrugs showed significant stability in normal tissues and …

bradford Repository record for Pharmacological investigations into matrix metalloproteinase-activated anti-tumour prodrugs. In vitro metabolic and pharmacological investigations into a series of colchicine-based peptide prodrugs activated by tumour-expressed matrix metalloproteinases (opens in a new tab)