Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Coincidence detection"”.
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Coincidence detection in the cochlear nucleus : implications for the coding of pitch
… mechanism for this extraction is cross-frequency coincidence detection (CD), in which a central neuron converts the degree of cross-frequency coincidence in the AN into a rate response by preferentially firing when its AN inputs across the tonotopic axis discharge in synchrony. We implemented a CD …
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Calcium dynamics in dendrites and spines of spiny neurons in the somatosensory ‘barrel’ cortex of the rat
… intervals revealed a precisely tuned coincidence detection mechanism for pre- and postsynaptic activity, coded in the peak Ca2+ transient amplitude. Linear, sub- and supralinear summation of the Ca2+ transients, depending on the time interval and the order of bAP and EPSP, was found. …
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The role of short term synamptic plasticity in temporal coding of neuronal networks
… processing namely, temporal integration and coincidence detection by modulating the input synaptic strength. This dissertation has two parts. First we study the effects of short term synaptic plasticity in enhancing coincidence detecting ability of neurons in the avian auditory brainstem. …
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Development of a new portable instrument for in-situ activity measurement of Radionuclides in Nuclear Medicine
… is the hardware of the new in-situ 4πβ(LS) − γ coincidence detection system is developed at ENEA in collaboration with Catania University and INFN-Catania section, for activity measurement of short half-lived radionuclides used in nuclear medicine. Whereas, the data analysis software of the ENEA …
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Processing Submillisecond Timing Differences in a Model Electrosensory System
… I investigated the central mechanism for detection of submillisecond spike time differences by recording from time comparator neurons (Small Cells) in the midbrain. Recording from Small Cells is challenging because their somas are small and relatively inaccessible. I therefore designed a …
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A microfluidic biosensor to electrically enumerate blood cells at point-of-care for infectious disease diagnosis and management
… two techniques. We have also characterized the coincidence detection and show that cell counting with coincidence detection improves the accuracy of the counting results. We have translated this technology to perform a complete blood cell (CBC) count from a drop of blood. The total leukocyte …
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Fret-Based Investigations of The Structure-Function Relationships In The Nmda Receptor
… of a co-agonist, its magnesium-block-based coincidence detection, its slow kinetics, its calcium permeability, its allosteric modulation, and its especially important functional roles in synaptic plasticity, excitotoxicity, and more. In recent years, a wealth of structural information has …
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Spatio-temporal representation of the pitch of complex tones in the auditory nerve and cochlear nucleus
… in the direction consistent with cross-frequency coincidence detection. We also measured the strength of the rate representation for the pitch of harmonic complex tones in CN units and found a few units that maintained salient pitch cues at high stimulus levels. However there was no obvious …
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ADVANCED CMOS SINGLE-PHOTON IMAGER ARCHITECTURES FOR QUANTUM AND SCIENTIFIC IMAGING APPLICATIONS
… for optical path delays and perform real-time coincidence detection, enabling a resolution increase of nearly two orders of magnitude while reducing acquisition times by over 10× compared to traditional scanning systems. Second, a hardware-friendly on-chip compression scheme is developed for …
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Manipulations of spike trains and their impact on synchrony analysis
… analytical expressions of the probability of coincidence detection after dithering. The effectiveness of spike dithering in creating surrogate data strongly depends on the dithering method and on the method of counting coincidences. Closed-form expressions and bounds are derived for the case …
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Feedback control of analog neurons and shunting inhibition in dendrites for bio-inspired neuromorphic systems.
… is shown to enable high-level computation like coincidence detection and direction selectivity. This approach offers an alternative to classical delay-and-compare models, potentially overcoming their limitations in processing high-speed stimuli. The adaptability of the shunting conductance …
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Characterising the early aggregation events of human lysozyme using single-molecule microscopy
… microscopy techniques including two-colour coincidence detection (TCCD) and fluorescence resonance energy transfer (FRET) to determine the oligomer population distributions present during the aggregation of HuL. Our data showed that HuL populates disordered small low-FRET oligomers (<10 …
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Development of single-molecules techniques to study native α-Synuclein aggregates
… their structure. In order to facilitate specific detection of αSyn species in complex biological fluids using single-molecule confocal microscopy, the amyloid binding dye was replaced with an αSyn antibody. The need for constitutivly active dyes to be used at low picomolar concentrations in order …
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A Three-Molecule Model of Structural Plasticity: the Role of the Rho family GTPases in Local Biochemical Computation in Dendrites
… thresholds reveals a unique heterosynaptic coincidence detection mechanism that allows for cooperative expression of structural plasticity when spines are close together, which in turn provides a putative mechanism for how neurons arrange structural modifications during learning.</p>