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Showing 1 to 7 of 7 for “"Cohesins"”.
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Insights into Shugoshin localization and function in S. cerevisiae chromosome segregation
… sister chromatids segregate during the second. Cohesins, protein complexes that associate along the length of chromosomes during DNA replication, are lost in a step-wise manner in meiosis. During the first division, cohesins are lost only along chromosome arms. Cohesins remain at centromeres …
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Functional characterisation of cohesin subunit SMC3 and separase and their roles in the segregation of large and minichromosomes in Trypanosoma brucei
… In separase-depleted mitotic cells, cohesins remained bound to chromatin, which is in contrast to rapid dissociation of cohesins from chromatin in wild-type mitotic cells. The severity of segregation phenotypes after separase depletion was additionally explained by defects in the …
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The examination of mechanisms underlying meiotic chromosome segregation
… independent of DNA replication, but depends on cohesins, actin filaments, SC components and DSBs.
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MODELING COHESIN-DEPENDENT ONCOGENESIS IN VITRO AND IN VIVO: POSSIBLE AMELIORATIVE EFFECTS OF PARP INHIBITION
… My data provide a model to study the role of cohesins and PARP inhibition in brain tumorigenesis and suggest that their combined impairment might cause synthetic lethality, highlighting a new tumor vulnerability.
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Patterns and processes driving chromosome organization
… different interactions between loop extruding Cohesins and Condensins. We find that non-trivial interactions between these complexes are required to accurately capture the dynamics of the data. Our findings extend the model of loop extrusion and highlight the role of interactions between SMC …
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Analysis of the S. pombe sister chromatid cohesin subunit in response to DNA damage agents during mitosis.
… Secondly, the main differences between the two cohesins are emphasised, in that both are solely expressed during alternative life cycles. During the course of a synchronous wild-type mitosis, northern analysis of rad21+ mRNA levels revealed that this cohesin subunit is periodically expressed …
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Cohesin Promotes the Myelination Transcriptional Program in Oligodendrocytes
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.