Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Coenzyme-Q10"”.
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The effect of oral coenzyme Q10 on the exercise tolerance of middle-aged, untrained men
There is no abstract available for this dissertation.
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Oxidative Stress and Inflammation in the Heterogeneity of Metabolic Health
… IL-6, soluble IL-6 receptor, C-reactive protein, coenzyme Q10, oxidized CoQ10, markers of oxidative damage, antioxidant capacity, and advanced glycation end products. Dietary patterns, physical activity, and gut microbiota composition were also evaluated. The findings indicate that metabolic …
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Cloning, Heterologous Expression, and Characterization of Human and Escherichia Coli Choline Dehydrogenases
… molecular oxygen, which has been proposed to be Coenzyme Q10 in mammals, based on studies performed with rat liver mitochondria and partially purified enzyme. As a first step towards a biochemical and mechanistic characterization of CHDH, both human and E. coli CHDH have been cloned and expressed …
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Regulation of the redox homeostasis during polyglutamine misfolding in Huntington’s Disease
… (L-NAC and Trolox). Moreover, the use of MitoQ (Coenzyme Q10 covalently attached to triphenylphosphonium cation (TPP+)) at nanomolar concentrations abrogated the increased ROS due to mhttEx1 suggesting a mitochondrial origin of ROS.<br/><br/>Given that molecular chaperones regulate the …
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Deconvoluting genetic variants associated with aortic disease using stem cell models
… high-throughput drug screening assay identified Coenzyme Q10 as improving contraction in wild type and SMAD4 VSMCs and MYLK mutant EVT active contraction was restored by targeting the Rho kinase pathway. A pipeline was established between national flagship population genomic studies and detailed …
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Cryo-EM studies of substrate and inhibitor binding to mammalian respiratory complex I
Mammalian respiratory complex I (NADH:ubiquinone oxidoreductase) is an intricate multi-subunit, energy-transducing membrane protein that is essential for aerobic energy metabolism and NADH/NAD⁺ homeostasis. It couples the energy released from NADH oxidation and ubiquinone (Q) reduction to pump four …