Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Codon choice"”.
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How codon choice determines evolvability and evolutionary robustness in short linear motifs
… that is defined from the nucleotide and codon levels. Simulations using this methodology suggested that different codons have varying propensities to evolve into amino acids within a linear motif. In other words, some sequences have higher motif evolvability. The simulations also …
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Synthesis, Characterisation and Evolution of Escherichia coli with a Compressed Genetic Code
… genomes with systematic removal of particular codons provide a unique opportunity to investigate rules that govern codon choice and enable the creation of organisms with a compressed genetic code. Such liberated codons can be reassigned to non-canonical amino acids to equip proteins with novel …
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Codon Usage Biases Differ Between Tissues and Can Confer Tissue-Specific Gene Expression in Drosophila
<p>Codon usage bias is a fundamental aspect of the genetic code. For many years synonymous mutations to a coding sequence were considered to be functionally “silent.” We now appreciate that is not the case and that synonymous codon choice can have drastic implications for gene expression and …
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Rewriting the genome of Escherichia coli
… is the creation of recoded genomes, where codons are substituted by their synonyms. Compression of synonymous codon boxes may provide blank spaces in the quasi-universal genetic code, and these may be amenable for reassignment into unnatural amino acids, in synergy with parallel efforts to …