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Showing 1 to 5 of 5 for “"Coagulation factor XIII"”.

  1. Roles of coagulation factor XIII in the functions of blood platelets

    Magwenzi, Simbarashe G.Hull York Medical School, the University of Hull and the University of York2011

    Activated blood coagulation factor XIII (FXIIIa) is a transglutaminase that stabilises fibrin clots and associates with platelets. In the present study, the role of factor XIII (FXIII) in modulating physiological platelet functional responses including adhesion, signal transduction and spreading …

    hull Repository record

  2. Roles of coagulation factor XIII in the functions of blood platelets

    Magwenzi, Simbarashe G.Hull York Medical School, the University of Hull and the University of York2011

    … concerted actions of blood platelets and soluble coagulation factors in forming blood clots at sites of vascular injury. Platelets are recruited from flowing blood and become activated to fulfil their haemostatic roles (Marcus, 1969, Ruggeri and Mendolicchio, 2007). Coagulation factors are also …

    hull Repository record

  3. Coagulation Factor XIII (FXIII) and Vascular Endothelial Growth Factors VEGF and VEGF-C Produced by Platelers : From Clinical Findings to Molecular Characteristics

    Wartiovaara, UllaHelsingin yliopisto1999

    helsinki Repository record

  4. Evaluation of the Role of Endogenous Factor XIII as a Determinant of Bleeding-Related Outcomes and Death Among Severely Injured Patients

    Gomez Builes, Johana Carolina2025

    … blood loss by reducing clot destruction with coagulation factors such as factor XIII (FXIII). Lower serum FXIII levels can cause reduced clot stability and premature clot breakdown. We hypothesize that lower FXIII levels result in worse bleeding-related outcomes and death. To test the …

    toronto-retro Repository record

  5. Design, Synthesis and Evaluation of Covalent Inhibitors for Tissue Transglutaminase and Factor XIIIa

    Akbar, AbdullahUniversité d'Ottawa / University of Ottawa2019

    … human tissue transglutaminase (hTG2) and human factor XIIIa (FXIIIa). Divided into two projects for each enzyme, the main objective of this thesis was directed towards the discovery of potent and selective covalent inhibitors for each isozyme, namely hTG2 and hFXIIIa. The first project was …

    ottawa-retro Repository record