Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 32 for “"Clinical events"”.
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Intelligent patient monitoring : detecting and defining significant clinical events
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1996.
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"I Just Knew" : Exploration of nurses' early perceptual recognition of life threatening clinical events
… and is an acquired skill. EPR may also improve clinical outcomes. Implications of this research include the need to develop teaching strategies that will help nurses and nursing students develop their EPR skills. Methods to assess the affect of EPR on clinical outcomes must also be developed.
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Biomechanical Analysis of Human Coronary Atherosclerotic Plaques in Response to Pharmacotherapy, and in Predicting Adverse Clinical Events
… plaques that subsequently developed adverse clinical events. Lumen roughness heterogeneity showed a weak correlation with PSS and was an independent predictor of adverse clinical events. Finally, the role of combined PSS and ESS in plaque risk prediction was assessed through a subgroup …
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Free text phrase encoding and information extraction from medical notes
… a large database of patient signals and clinical data from critically ill patients in hospital intensive care units (ICUs). The data will be used as a research resource to support the development of an advanced patient monitoring system for ICUs. Important pathophysiologic events in the …
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Investigation Into The Role Of Biomechanical Forces In Determining The Behaviour of Coronary Atherosclerotic Plaques
… plaque precipitates the majority of these clinical events, resulting in thrombosis and myocardial infarction. Post-mortem studies have identified thin-cap fibroatheroma (TCFA) as the plaque subtype most prone to rupture with prospective virtual-histology intravascular ultrasound (VH-IVUS) …
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Operating room fire management simulation and instructional video
… to experience high-impact, low-frequency (HILF) clinical events that they may not experience during their clinical training. Practicing these infrequent but potentially catastrophic scenarios supports the development of deliberate practice skills. The purpose of this project is to develop an …
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Duration of oral anticoagulation in first-episode idiopathic deep vein thrombosis: A Markov decision analysis.
… three months to lifelong. The probabilities of clinical events were extracted from a systematic review of the literature on duration of therapy for DVT as well as rates of bleeding secondary to anticoagulant therapy and rates of developing post-thrombotic syndrome. Utilities for each of the …
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Sickle cell anaemia in Cameroon : co-inheritance of α-thalassemia, HBB gene haplotypes, clinical & haematological characterisations
… patients can manifest varying degrees of clinical severity due to various genetic modulators that affect the phenotype of this disease. The co-inheritance of alpha-thalassemia (α-thalassemia) has been associated with a milder phenotype in SCA patients (e.g. lower stoke rate), but could …
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The development of a neonatal vital signs database
… these algorithms. In order to develop robust and clinically valid algorithms, a database of representative waveforms is required. The aim of this thesis was to create a neonatal vital signs database to be used for this purpose, by means of a computer-based central station. The computer was …
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Clinical outcome and Predictive factors of Coronary aneurysm after Percutaneous Coronary Intervention
… findings may be related with adverse clinical events because recent DES registry data showed CAAs took mostly favorable clinical courses with continuous dual-antiplatelet therapy (Ahn et al., 2010) although poor clinical outcomes including in-stent restenosis and stent thrombosis after …
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A Theoretical Model Of Breast Tumor Metastases In The Context Of Tumor Dormancy
… cancer decision-analytic model that integrates a clinical model and a tumor progression model which incorporates primary tumor growth, dissemination of tumor cells into the circulatory system, tumor cell dormancy period at the distant site, and metastasis growth. The flexible model structure …
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Real-time analysis of physiological data and development of alarm algorithms for patient monitoring in the Intensive Care Unit
… a well-annotated data set. In previous studies, clinical events were either unavailable or annotated without accurate time synchronization with physiological signals, generating uncertainties during both the development and evaluation of intelligent alarm algorithms. This research aims to help …
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Dynamic Prediction of Disease Progression With Longitudinal Data
<p>Dynamic prediction plays a pivotal role in clinical research, especially when forecasting time-to-event outcomes based on evolving longitudinal data. This process often leverages the integration of longitudinal and time-to-event data through joint modeling, a prevalent technique. Alongside joint …
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Health-Related Quality of Life in Children with Cancer
… These time-points reflected significant clinical events that reflected change in the intensity or modality of treatments. Our analysis identified significant changes across different diagnostic groups and over time in HRQOL of children undergoing curative cancer treatments. Time in …
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Use of the Non-Pneumatic Anti-Shock Garment (NASG) For Life-Threatening Obstetric Hemorrhage: A Cost-Effectiveness Analysis in Egypt and Nigeria
… data from pre-intervention/NASG-intervention clinical trials with costs from study sites. For each country, we used observed proportions of initial shock level (mild: mean arterial pressure [MAP] > 60mmHg; severe: MAP ≤ 60mmHg) to define a standard population of 1,000 women presenting in …
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Correlation of Macroscopic and Microscopic Placental Lesions with Obstetric and Neonatal Outcomes in an unselected Population
… does exist between the placental lesion and the clinical event. Relationships between “lower grade” placental lesions and clinical outcomes are less clear. Reports of associations between selected abnormalities and clinical outcomes are largely based on retrospective case control studies: the …
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Extending the clinical and economic evaluations of a randomised controlled trial: The IONA Study
… come to market it has to be proved to be both clinically effective and economically cost-effective. With limited health care resources the cost-effectiveness of treatments is becoming ever more relevant. In order to show whether a treatment is clinically effective a clinical trial is carried …
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Molecular imaging of calcification and inflammation in aortic valve disease and atherosclerosis
… pharmacology was elaborated. In observational clinical studies, 18F-fluoride and 18F-FDG uptake in aortic valvular, coronary and carotid arterial tissue was assessed. Techniques for uptake quantification were evaluated for accuracy and reliability. Tissue uptake was related to established …
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Identifying Vulnerable Plaques with Acoustic Radiation Force Impulse Imaging
… the treatment of stroke before the onset of clinical events.</p><p>This dissertation evaluates the hypothesis that Acoustic Radiation Force Impulse (ARFI) imaging can noninvasively identify lipid regions, that have been shown to increase a plaque's propensity to rupture, within carotid artery …
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Three-dimensional Quantitative Magnetic Resonance Imaging of Carotid Atherosclerotic Plaque
… have shown correlations with subsequent clinical events. High resolution, multi-contrast magnetic resonance imaging (MRI) can qualitatively identify these features and monitor disease progression. Compared to traditional contrast weighted imaging, quantitative MRI could provide an …
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