Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 421 for “"Clinical data"”.
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Constructing decision models for diabetes using clinical data
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1994.
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Machine learning for digital health: Transforming clinical data into knowledge
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-04-12 without embargo terms
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Optimizing Machine Learning Performance on Tabular Clinical Data: A Pipeline Approach
… learning solutions for mixed-type tabular clinical data. Such datasets, prevalent in healthcare, are characterized by a complex interplay of numerical and categorical features, often leading to intricate, non-linear dependencies that hinder traditional analysis and model efficacy. …
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Integrating Serial Quantitative Imaging with Clinical Data to Predict Brain Hemorrhage Outcomes
… routinely used to diagnose, monitor, and inform clinical decisions in patients with brain hemorrhage. Subarachnoid hemorrhage (SAH) is a devastating form of brain hemorrhage in which blood erupts into the space surrounding the brain, potentially leading to severe neurologic complications, such as …
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Informatics Approaches to Linking Mutations to Biological Pathways, Networks and Clinical Data
… This makes SNPs as well other genetic variation data of great value for biomedical research and for developing pharmaceutical products or medical diagnostics. The goal of the project is to link genetic variation data to biological pathways and networks data, and also to clinical data for creating …
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COVID-19 Therapeutics – A landscape analysis using systematic reviews and clinical data
… necessity of the scientific community to share data and insights generated worldwide. One of the potential unintended consequences of the sheer volume of literature in such a short amount of time is that many of it is not carefully peer-reviewed and vetted, making it difficult to sieve through …
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Non-parametric Parameter Estimation and Clinical Data Fitting with a Model of HIV Infection
… and statistical modeling approach for analyzing clinical data from an HIV acute infection study. We amalgamate two existing models from the literature to create a nonlinear differential equation model of in-host infection dynamics that is capable of predicting sustained low-level viral loads and …
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Computational Approaches to Understand Chemoresistance & Tumor Evolution Using Longitudinal Clinical Data and Lineage Tracing
… tumor profiling from an ongoing randomized clinical trial in triple-negative breast cancer (ARTEMIS) to assess mechanisms of chemo-resistance, and use longitudinally tracked patient biopsies to interrogate patterns of response and evolution under chemotherapy. We performed comprehensive …
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Intestinal Adaptation to Repeated Exposure of Flavonoid-rich Foods: In Vitro and Clinical Data
… addition to use of <em>in vitro</em> models and clinical work to test the effect of repeated exposure on flavonoid bioavailability.</p> <p>Though flavan-3-ols undergo Phase II metabolism in humans and rodents, researchers have generally not been able to utilize fully characterized standards for …
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The Interpretation of Objectively Measured Personality Factors in Terms of Clinical Data and Concepts
Made available in DSpace on 2014-12-08T23:01:42Z (GMT). No. of bitstreams: 1 6801867.pdf: 14978647 bytes, checksum: ce5de739c9abd39f5697e61a4fc57e71 (MD5) Previous issue date: 1967
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Novel combination strategies with Aurora Kinase Inhibitors: using pre-clinical data to guide clinical trial design
… drugs with aurora kinase inhibitors (AKI) in pre-clinical models and then to design a clinical trial to assess these in patients with bladder cancer. Particular interest was stimulated by the correlation between over-expression of aurora kinases (AKs) with aggressive clinical behaviour in many …
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Resting-State Cerebral Perfusion Patterns: An Exploratory Factor Analysis of Single-Photon Emission Computed Tomography Clinical Data
… describe human RS rCBF patterns in persons with clinical neuropathologies and psychopathologies using SPECT. A robust exploratory factor analysis (EFA) of 12,217 clinical participants was implemented with techniques to increase reliability and replicability, such as parallel and bootstrapped …
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Application of Informatics Tools to Facilitate the Practice of Precision Medicine with Genomic Testing and Clinical Data
… care. Factors such as patient demographics, clinical history, and lab test values have well understood effects on treatment outcomes and influence decision making. However, effective inclusion of biomolecular data such as protein expression and DNA sequencing data within the practice of …
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Combination of CT-based Radiomics Features and Clinical Data for Predicting Tumor Genetic Profile in patients with Intrahepatic Cholangiocarcinoma
… (20/90), IDH1 (10/58), and KRAS (9/58). Combined clinical-radiomic models showed the best performance in predicting FGFR2 (AUC = 0.892) and IDH1 status (AUC = 0.819), outperforming clinical or radiomic models alone. The radiomic model for KRAS mutations achieved an AUC of 0.767, compared to 0.660 …
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Developing a predictive model for factors related to risk of aggression in psychiatric inpatients using physiological and clinical data
… during psychiatric stays, the study employs big data analysis on an actual clinical data set extracted from patients’ medical records to develop a predictive model for clinical aggression risk factors. Retrospective analysis covers variables such as heart rate, blood pressure, age, incidents, …
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Can we predict when to start renal replacement therapy in chronic kidney disease patient by using 6 months clinical data?
… renal replacement therapy (RRT), using 6 months clinical data variables routinely measured in healthcare centers. METHODS: The data were derived from the electronic medical records (EMR) at Ajou University Hospital, Suwon, South Korea from October 1997 to September 2012. We included patients who …
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