Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 18 of 18 for “"Clinical Therapy"”.
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Dissecting the Role of ATRX in Soft Tissue Sarcoma Development and Therapeutic Response
… and increases sarcoma sensitivity to radiation therapy. In the absence of Atrx, irradiated sarcomas have increased persistent DNA damage, telomere dysfunction, and mitotic catastrophe. We find that Atrx deleted tumors have impaired cGAS-STING signaling, with accompanying sensitivity to the novel …
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Perspective
… within the universe. Rooted in meditation and therapy, the project uses the seven Chakras and clinical therapy methods to shape spaces that promoteintrospection and personal growth. Set in the Rocky Mountains nearDenver, the retreat's design responds to the natural terrain, using views,light, …
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A study into the properties and applications of bacterial microcompartments and polyphosphate metabolism
… were defined, and potential applications as a clinical therapy addressed in an animal trial, which utilized the phosphate-uptake constructs which had been created. In the trial, recombinant bacteria expressing these constructs were successfully delivered in therapeutic quantities to the target …
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A case study on the social and economic experiences of the children of the liberation struggle at Berg Aukas camp in Grootfontein, Otjozondjupa region
… psychosocial support. The study recommends clinical therapy, psychological support and counselling for all the interviewed CLS.
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The Relationship between Psychotherapist Personality and Therapeutic Alliance
<p>Time-limited effective psychotherapy is a topic that is frequently addressed in clinical therapy research. Though a wide range of therapeutic factors, expectancy effects, techniques, and extratherapeutic have all been demonstrated to be related to outcome, researchers have consistently …
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Analysis, design and use of a Fourier-transform spectrometer for near infrared glucose absorption measurement
… glucose monitoring is a long pursued goal in clinical therapy as an invaluable tool that would aid in the treatment of diabetes. The importance of such device is marked by the market value of glucose testing devices, which was estimated to be more than $2.5 billion worldwide in 1997, and …
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Four investigations of arising phenomena in contemporary work settings: the cases of mindfulness practices and crowdworking online platforms
… Rooted in spirituality and formerly used in clinical therapy, mindfulness is applied as a human resource development practice to train employees and managers to cope with the increased work intensification. Second, digitization and the importance of individualization opened up the path for …
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Oxygen resuscitation does not ameliorate neonatal hypoxia/ischemia-induced edema
… treatment after HI (HHI) is the recommended clinical therapy for newborn resuscitation. Our objective was to evaluate edema development after HI and whether HHI treatment affected HI-induced edema. We induced HI by a permanent ligation of the left carotid artery followed by a systemic …
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Microrna Regulation of Prostate Cancer Stem/Progenitor Cells and Prostate Cancer Development
… establishment, metastasis, and resistance to clinical therapy. It’s crucial to understand the regulatory mechanisms unique to CSCs, so that we may design CSC-specific therapeutics. Recent discoveries of microRNA (miRNA) have provided a new avenue in understanding the regulatory mechanisms of …
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Bioactivity evaluation of peptide QUB-1480 from the skin secretion of the Green Cascade frog (Odorrana livida)
… or anticancer agents to be used in the clinical therapy. Because of the inhibitory activity against E. coli, QUB-1480 is expected to lower the dose of the antibiotics to a large extent. At the same time, QUB-1480 may be used with colon cancer medicine such as Oxaliplatin to lower the …
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Studio di complessi di rame (II) e platino (II) con proprietà antitumorali
… is one of the most active drugs in anticancer therapy, and it is currently used for the treatment of a wide range of cancers, in particular advanced ones. After its introduction in clinical therapy, the research in this field has focused on the preparation of new metal complexes with increased …
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Trabecular Calcium Phosphate Scaffolds for Bone Regeneration
… bone in the body. The science underlying this clinical therapy bridges the traditional fields of cell biology, materials science and mechanical engineering with the aim to identify how cells behave on physiologically relevant materials with natural mechanical stimuli. The objectives of this …
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Injectable hydrogels for the improved delivery of treatments in spinal cord injury
… with chronic medical consequences. Although no clinical therapy is currently available to reverse paralysis, a number of biomacromolecule drug candidates in the form of proteins, enzymes and monoclonal antibodies have demonstrated restoration of function in studies with SC animal models. …
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Computational models for respiratory gas exchange and their applications
… experimentation/imaging, and gas exchange during clinical therapy. First, the simplest steady state model is used to study structure-function relationships in the normal lung and reconcile differing experimental observations on the relative importance of passive ventilation-perfusion matching …
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Development of biomimetic microfluidic adhesive substrates for cell separation
… is important in medical, biological research, clinical therapy, diagnostics and many other areas. The conventional methods of cell sorting have limited applications due to sophisticated equipment settings, high costs, or time-intensive and labor-intensive processing steps. Inspired from natural …
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Synthesis and Evaluation of Carbohydrate Based Cationic Polymers for siRNA Delivery and Tracking
… become the bottleneck in both laboratory use and clinical therapy in the future. In general, the small interfering RNA molecules as well as other RNA molecules have poor pharmacokinetic profiles, can easily be hydrolyzed or degraded, cause serious immunogenic response and can be toxic to …
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The role of IL-27 and IL-35 in inflammatory diseases
… human RA should be carefully investigated before clinical therapy application.