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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 293 for “"Clinical Research"”.
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A Relational Account of Exploitation in Clinical Research
… as an important concept that limits how clinical research is conducted. Yet, there is disagreement at nearly every level regarding the source of wrongness of exploitation, its connection to injustice, and the practical importance of exploitation. This dissertation considers whether the …
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A Naturalistic and Inductive Methodology for Clinical Research
Made available in DSpace on 2014-12-12T19:55:35Z (GMT). No. of bitstreams: 1 7913395.pdf: 7128469 bytes, checksum: c70b9207ead5f9856ea632340ae275b4 (MD5) Previous issue date: 1978
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Addressing Potential Exploitation In Clinical Research on Human Subjects
Numerous claims have been made to the effect that clinical research on human subjects can be exploitative — and hence morally problematic — even if there is informed consent and in the absence of any harm. If such claims are true, it follows that research ethics bodies ought to include avoidance of …
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Clinical Research with Pregnant Women: Investigator Insights on Success
The lack of clinical research in pregnancy negatively impacts the ability to provide therapeutic treatments and preventions to pregnant women. This study explores the experiences of investigators who have successfully conducted clinical research in pregnancy to identify factors that facilitate …
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Reproducibility and reliability of chromatin immunoprecipitation in clinical research
… been able to demonstrate consistent results in a clinical population using white blood cells. It was established, for the first time, the normal variability of ChIP results in THP-1 cells, Jurkat cells, TF-1a, and human male circulating leukocytes over time for histone modifications H3k4me3 and …
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Utilization of opt-out registries in emergency clinical research
<p>Background: Emergency clinical research aims to study and develop new treatments for acute injuries and illnesses such as stroke, traumatic brain injury, seizures, and meningitis. While the regulations require that researchers provide information about ways in which individuals wishing to be …
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The Feasibility of Clinical Research in Undergraduate Dental Outreach
… in which to support the conduction of clinical research studies.<b><br/></b><b><br/></b><b>Methods</b>: In order to test the ability to carry out clinical research in dental outreach clinics, a simple trial was set up to be conducted in outreach clinics. The Dental Outreach Oral Hygiene …
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Engaging Underserved Populations in Clinical Research Utilizing Conceptual Bioethical Priniciples
Minority underrepresentation in clinical research is an ongoing dilemma that is an impediment to discovering the most innovative therapies for all patients. Additionally, the lack of engagement of underserved minority populations in clinical research limits these patients to traditional standard of …
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Demographic profiles of clinical research participants in FDA-approved NMEs
… Recruitment and retention of human subjects in clinical trials is challenging. This study collected the demographics of trial participant in trials for New Molecular Entities (NMEs) approved by the U.S. Food Drug Administration (FDA) for 2010 and 2020 to compare demographic representation. …
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Influence of clinical research investigator fraud on clinical trial participation
<p>The number of clinical research investigators whom the Food and Drug Administration (FDA) has disqualified or totally restricted has been increasing since 1964. In addition, several public polls and surveys indicate a major dilemma in clinical trial participation and public perceptions of …
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Are first generation immigrants more inclined to participate in clinical research?
… and ethnic groups are underrepresented in research studies. This study examined first- and second-generation Arab American immigrants in Dearborn, Michigan, using a survey from 65 participants to determine the impact of generation on clinical research participation. Fifty-one (78%) of the …
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Are clinical research professionals more inclined to participate in clinical trials?
… and education on a willingness to participate in clinical trials. It hypothesized that there is no statistical difference in the median rank score between clinical research professionals and other post-graduate educated participants. The research question asked whether the clinical research …
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The Role of a Clinical Research Nurse: The Impact of Working Remotely
Clinical research nurses (CRNs) are an integral part of clinical trials and have a responsibility to care for research patients, collaborate within multidisciplinary teams, and manage protocol adherence. CRNs are often the hub of a multidisciplinary research team, and it is important to understand …
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An investigation of set shifting in anorexia nervosa and clinical research portfolio
Background: Recent research has examined the possibilities that deficits in cognitive processes, in particular set shifting, might contribute to the development and maintenance of anorexia nervosa (AN). Results of studies of set shifting have been mixed. There has been considerable variability in …
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Demographic profile of clinical research volunteers: Improving the effectiveness of promotional recruitment
… Successfully recruiting participants for clinical trials is a challenge that crosses all medical disciplines. Slow enrollment to clinical trials delays the completion of clinical research studies.</p> <p>Objectives: This study collected demographic data of current and past clinical trial …
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Improved access to large medical databases for clinical research and quality improvement
… Information is routinely stored for each clinical encounter, be it an inpatient, outpatient, telephone, or even computer-based interaction. In the past, the vast majority of this data concerned the demographic and financial details of the encounter; however, more and more clinically …
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Privacy and identifiability in clinical research, personalized medicine, and public health surveillance
… health information has become pervasive in research, clinical, and public health investigations, posing substantial risk to patient privacy. From clinical genetic screenings to publication of data in research studies, these activities have the potential to disclose identity, medical …
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An exploration of parametric versus nonparametric statistics in occupational therapy clinical research
Data sets from research in clinical practice professions often do not meet assumptions necessary for appropriate use of parametric statistics (Lezak and Gray, 1984). When assumptions underlying the use of the parametric tests are violated or cannot be documented, the power of the parametric test …
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Variables that affect the amount of the consent that clinical research subjects read
… subjects to insure that their participation in clinical drug studies is informed as well as voluntary. Recently questions have been raised as to whether written consent forms guarantee participants are making autonomous, informed decisions. The purpose of this study was to determine how much of …
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