Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 390 for “"Class I"”.
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Structure and function of class I diterpene synthase
… This bifunctional enzyme catalyzes both class I (ionization-initiated), as well as class II (protonation initiated) cyclization reactions, and is composed of three α-helical domains, designated α, β, and γ, wherein the class I active site falls within the C-terminal α domain and the class …
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Quantifying Impacts of Class I Milk Price Formula Reform: A Study of FMMO Uniform Milk Price Volatility and Class I Milk Hedging
… Bill and enacted beginning with the May 2019 Class I milk price. The newly reformed formula was designed to strengthen the price relationship between available CME futures contracts and Advanced Class I skim milk prices without having a long-term directional influence on average Advanced Class …
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Amino acid recognition by a Class I tRNA synthetase
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1996.
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A Cephalometric Evaluation of Variations of Angle Class I Malocclusions
Indiana University-Purdue University Indianapolis (IUPUI)
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Investigating the role of HLA class I derived peptide in alloreactivity.
… peptides which are themselves derived from HLA class I molecules, which may have a role in the alloresponses, within the context of clinical transplantation.This research describes the creation of a database of HLA class I derived peptides predicted to bind to HLA-A*02 molecules, and then …
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Regulation of Metabolic Processes by Micrornas and Class I Histone Deacetylases
Obesity is a medical condition resulting from accumulation of excess body fat that affects more than 30% of the adult population in the U.S. Obesity-related pathological conditions include heart disease, stroke, type 2 diabetes and certain types of cancer. Despite the high incidence and the …
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Singular Integral Equations With Symmetric Complex-Valued Kernels of Class I
Made available in DSpace on 2014-12-05T21:50:01Z (GMT). No. of bitstreams: 1 0009163.pdf: 1228558 bytes, checksum: cbcd267d7bd50fd799154aa77f9bf52b (MD5) Previous issue date: 1954
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Mechanistic studies of the Class I ribonucleotide reductase from Escherichia coli
… required for DNA replication and repair. The class I RNRs are found in many bacteria, DNA viruses, and all eukaryotes including humans, and are composed of two homodimeric subunits: R1 and R2. RNR from Escherichia coli (E. coli ) serves as the prototype of this class. R1 has the active site …
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Control of major histocompatibility Class I antigen expression in adenovirus transformed cells.
… of the Major Histocompatibility Complex (MHC) class I gene have been shown to play an important role in controlling transcription of this gene. MHC class I expression is down-regulated in cells expressing Adenovirus (Ad) 12 E1A compared to cells expressing E1A from Ad2 or Ad5. The possible …
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The Role of Class I Histone Deacetylases in Cardiovascular Development and Disease
… largely unexplored. Genetic studies have shown class II HDACs regulate developmental and physiological processes through the interaction with and repression of myocyte enhancer factor 2, MEF2, however the biological functions of class I HDACs have not been determined. To potentially understand …
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Slope Stability Analysis Of Class I Landfills With Co Disposal Of Bios
… of biosolids on the geotechnical properties of class I landfill as determined from field investigations. The geotechnical properties are evaluated using an in-situ deep exploration test, called the Cone Penetration Test (CPT). CPT provides a continuous log of subsurface material properties using …
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Molecular basis of TAPBPR-mediated peptide editing on MHC class I molecules
Major histocompatibility complex (MHC) class I molecules present fragments of the cellular proteome, in the form of short peptides, to the cell surface for the inspection by cytotoxic T cells. This process is a crucial immunosurveillance mechanism used to induce appropriate immune responses against …
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Associations between MHC class I variation and blood pathogen prevalence in caracal
… of species with respect to disease. MHC class I loci mediate the immune system's recognition of intracellular pathogens, including protozoans, viruses and bacteria, and the high levels of genetic diversity reported at these loci is thought to be primarily the result of pathogen-mediated …
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High-throughput profiling of viral class I fusion proteins via mammalian antigen display
Viral infections, particularly epidemics and pandemics, pose a significant threat to global health, causing substantial morbidity, mortality, and socioeconomic disruption. Moreover, viruses can cause chronic disease long after initial infection. While modern technologies enable early outbreak …
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High-throughput profiling of viral class I fusion proteins via mammalian antigen display
Viral infections, particularly epidemics and pandemics, pose a significant threat to global health, causing substantial morbidity, mortality, and socioeconomic disruption. Moreover, viruses can cause chronic disease long after initial infection. While modern technologies enable early outbreak …
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Characterization of antigen processing and presentation by peptide-linked MHC class I molecules
MHC-Klasse-I-Moleküle präsentieren gewöhnlich Peptide, die aus zytosolischen Antigenproteinen durch proteasomalen Verdau generiert und anschließend vom TAP-Peptidtransporter ins endoplasmatische Retikulum transportiert werden. Es können jedoch auch endozytierte Antigene für die …
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Modulation of Ly49A+ Natural Killer Cell Licensing by Major Histocompatibility Complex Class I Alleles
… self-MHC: major histocompatibility complex) class I molecules, such as transformed or virally infected host cells and allogeneic bone marrow. This reactivity is mediated by inhibitory receptors for MHC class I that block the ability of activation receptors to stimulate NK cells. Since many NK …
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