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Showing 1 to 3 of 3 for “"ClC-2"”.
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Der spannungsgesteuerte Chloridkanal CIC-2 und seine Bedeutung in der Pathogenese von idiopathischer generalisierter Epilepsie
ClC-2 is a member of the ClC-family of voltage-gated chloride channels. Within this family, ClC-2 is unique in being activated by hyperpolarization, low extracellular pH and hypotonic cell swelling. In this study, several biophysical properties of the human ClC-2 channel have been functionally …
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Mechanisms of Prostaglandin-Stimulated Recovery of Mucosal Barrier Function in the Ischemia-Injured Porcine Intestine: Role of Intestinal Ion Transport
… results from these studies demonstrate that ClC-2-mediated intestinal Cl- secretion restores TER in ischemia-injured intestine. Chapter IV entails a study aimed at more directly investigating the role of ClC-2 in mucosal repair by evaluating mucosal repair in ischemia-injured intestinal …
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Ionenkanäle während der Nephrogenese
… ENaC-Natrium-Kanals und der Chlorid-Kanäle CFTR, CLC-2 und ICLn mittels RT-PCR im Sammelrohrepithel quantifiziert. Alle Experimente wurden an Ratten oder Mäusen durchgeführt. Ergebnisse: (i) Die mRNA der KDNP-(KATP)-Kanaluntereinheiten Kir6.1/SUR2 war in frühen Ureterknospen-Generationen …