Global ETD Search
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Showing 1 to 12 of 12 for “"Citalopram"”.
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Mechanisms of platelet inhibition by the selective serotonin reuptake inhibitor citalopram
… in vitro experimental data is limited. The SSRI citalopram is a racemate, the (S)-isomer being the more potent SERT inhibitor. Although citalopram has been shown to inhibit platelets in vitro, it is unclear whether this is mediated via SERT blockade. Aim: To determine if citalopram inhibits …
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Monoamine Transporter Photoaffinity Ligands Based On Methylphenidate and Citalopram: Rational Design, Chemical Synthesis, and Biochemical Application
… probes based on methylphenidate (MP) and citalopram (CIT), two therapeutically significant MAT inhibitors, in order to map their binding sites and poses within their major MAT target protein. The central hypothesis was that MP and CIT could be rationally derivatized, without significant …
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The Effect of SSRIs on Adult Human Visual Cortex Plasticity. Do SSRIs Affect learning?
… in a crossover study whereby placebo and citalopram were each combined with two weeks of occlusion therapy. Visual acuity (VA), stereopsis, electroretinograms and visual evoked potentials (VEPs) were measured fortnightly. The third experiment was a case study in which one participant with …
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Arzneimittelsicherheit in der Psychiatrie
… Therapien mit dem enantioselektiven Wirkstoff Escitalopram sowie mit dem razematischen Arzneistoff Citalopram unter klinischen Alltagsbedingungen vergleichend untersucht. Ausgewertet werden die Daten des Projektes Arzneimittelsicherheit in der Psychiatrie (AMSP). Dieses ist ein unabhängiges, …
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Pharmacist input into patients' self-reporting of adverse drug reactions.
… fentanyl patch, venlafaxine, nefazodone, citalopram, moclobemide, gabapentin, lamotrigine and topiramate from 79 participating medical practices in Grampian during January-March 1997. The overall response rates were 44.6% (n=207) for the pilot study and 36.3% (n=837) for the main study. …
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Die Wirkung von Serotonin-Wiederaufnahmehemmern auf Ca 2 +-Ströme in hippocampalen CA1 Pyramidenzellen der Ratte
… in verschiedenem Ausmaße Ca2+-Kanäle blockieren. Citalopram zeigte keinen Effekt auf Ca2+-Ströme. <br>Die Substanzen Fluoxetin und Fluvoxamin wurden genauer betrachtet. Fluoxetin blockiert v.a. Kanäle der Cav2.2 (N-Typ)-Familie. Fluvoxamin hingegen blockiert Cav1,2.1,2.2, 3 (L-, P/Q-, N-, …
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Microbial and Immune Signatures of Stress and Antidepressants Across Sex and Generations
… structure of their dams, and that perinatal citalopram treatment produced stronger and more persistent effects in female offspring than in males. These findings reveal that stress and antidepressant exposure interact with sex and developmental stage to shape gut microbial composition and …
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Serotonin and Threat: from Gene to Behaviour
… a selective serotonin reuptake inhibitor (SSRI), citalopram reduced key characteristics of the high trait anxious phenotype: high state anxiety, and both the behavioural and physiological expression of conditioned fear. Anatomically, high anxious animals showed reduced basolateral amygdala (BLA) …
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Performance of septic tanks for pharmaceutical removal and their impact to river water quality.
… was for example found for fluoxetine, naproxen, citalopram, omeprazole, and cotinine. The similar enantiomeric composition of ST influent and effluent suggests that unlike in aerobic WWTWs, no enantioselective degradation occurs in STs. Potentially, the unchanged enantiomeric composition in ST …
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Neurodevelopmental and Behavioral Consequences of Serotonin System Disruption via Early Life Exposure to SSRI Antidepressants
… here show that perinatal exposure to the SSRI citalopram increases mRNA expression of Bai3 and related molecules (including its C1ql ligands) in the early postnatal dentate gyrus of male and female offspring. Transient Bai3 mRNA knockdown in perinatal SSRI-exposed dentate gyrus lessened …
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Developing an in-depth understanding of the prevalence, risk factors and treatment recommendations for phantom limb pain, and patient-generated care priorities for people who have undergone lower limb amputations
… for managing PLP, and on two treatments [citalopram (60%) and Pulsed Radiofrequency Stimulation of the dorsal root ganglion (70%)] that were considered ineffective. In the patient Delphi study, consensus was reached on 24 short-term care priorities and 12 long-term care priorities. The …
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Depression in glioma
… at T1, 7.4% ± 4.9% at T2 and 12.6% ± 6.9% at T3. Citalopram was the most frequent antidepressant choice. Antidepressant tolerability appeared to be good among patients who could be followed up. [5] Barriers to the management of depression included 78.4% of GPs regarding major depression as a …