Global ETD Search
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Showing 1 to 2 of 2 for “"Cisternal Maturation"”.
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Elucidating the role of TM9SF2 in membrane trafficking
… of glycosyltransferases within the Golgi. The cisternal maturation model proposes that cisternae progress through the Golgi, acquiring the necessary components as required. In theory, this would lead to resident Golgi enzymes becoming mislocalised. One mechanism to prevent enzyme …
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Investigating the trafficking of Golgi-resident glycosylation enzymes
The Golgi is a major site of glycan processing mediated by a large number of Golgi-resident glycosylation enzymes. These enzymes are largely type II transmembrane domain (TMD) proteins consisting of a short N-terminal cytosolic tail, a short TMD and a lumenal ‘stem’ region which separates the …