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Showing 1 to 2 of 2 for “"Cisplatin-Chemistry"”.
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The Reaction of a Water Soluble Platinum Compound with Methionine and Derivatives
… complexes are a recent area of emphasis of cisplatin chemistry. The water soluble complexes could have a reduced toxicity compared with cisplatin. Oxaliplatin, which has an oxalate leaving group, has previously been shown to have less nephro-toxicity and higher water solubility than …
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Reactions of Platinum(II) Compounds with Selenium Containing Amino Acids
<p>Platinum(II) anticancer medications essentially react with DNA forming kinks in<br />the double helix of DNA and causing apoptosis. It has also been noted that these<br />anticancer medications react with methionine and cysteine in the body. With the new discoveries of selenium containing amino …